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Gene Expression Data
Assay Details
Assay
Reference: J:3904 Deltour L, et al., Differential expression of the two nonallelic proinsulin genes in the developing mouse embryo. Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):527-31
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5614667
Gene symbol: Ins2
Gene name: insulin II
Antibody: anti-proinsulin II
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: Tissue was fixed in Bouin-Hollande sublimate. It was embedded in paraplast.
Results
Specimen 4C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: islets of Langerhans Present Regionally restricted 4C Expression is found in the central area.
Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pancreas Present Regionally restricted Expression is confined to islet cell clusters. It is not seen elsewhere in the embryo.
Specimen 4E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pancreas Present Regionally restricted 4E Expression is confined to islet cell clusters. It is not seen elsewhere in the embryo.
Specimen not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: pancreas primordium dorsal bud Present Expression is not seen elsewhere in the embryo.
TS19: pancreas primordium ventral bud Present Expression is not seen elsewhere in the embryo.
Specimen 4G: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: pancreas primordium Present Single cells 4G Expression is easily detected in several cells in the epithelial lining of the cap-like dorsal anlage of the pancreas. Additional expression was occasionally seen in the wall of the ducts. It is not seen elsewhere in the embryo.
Specimen not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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