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Gene Expression Data
Assay Details
Assay
Reference: J:82110 Luukko K, et al., Identification of a novel putative signaling center, the tertiary enamel knot in the postnatal mouse molar tooth. Mech Dev. 2003 Mar;120(3):270-6
Assay type: RNA in situ
MGI Accession ID: MGI:5604524
Gene symbol: Slit1
Gene name: slit guidance ligand 1
Probe: Slit1 cDNA3
Probe preparation: Antisense labelled with S35 RNA
Assay notes: Fixative was 12.5% ethylenediaminetetraacetic acid (EDTA), 2.5% phosphonoformatic acid (PFA).
Results
Specimen 1C: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: lower jaw molar enamel organ Present Regionally restricted 1C Expression is in the lingual and buccal secondary enamel knot and in stellate reticulum cells between the knots.
TS24: secondary enamel knot Present 1C
TS24: early bell stage tooth Present Regionally restricted 1C

Specimen 1E/F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: stratum intermedium Present Regionally restricted 1E/F Expression is in cells between the cusps.
TS26: secondary enamel knot Present 1E/F
TS26: stellate reticulum Present 1E/F
TS26: lower jaw molar enamel organ Present 1E/F

Specimen 1G/H: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: lower jaw molar Present Regionally restricted 1G/H Expression is in the tertiary enamel knot on the mesial side of the lingual cusp tip.
TS27: stellate reticulum Present 1G/H
TS27: stratum intermedium Present 1G/H
TS27: tertiary enamel knot Present 1G/H

Specimen 1I/J: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: lower jaw molar Present Regionally restricted 1I/J Expression is in the tertiary enamel knot under the cusp tip and in adjacent epithelial cells.
TS27: tertiary enamel knot Present 1I/J

Specimen 1K/L: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: lower jaw molar Present Regionally restricted 1K/L Expression is between the cusp tips.

Specimen 1M: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: molar enamel organ Present Regionally restricted 1N/O , 1M Expression is in the tertiary enamel knot on the mesial side of each cusp tips.
TS28: tertiary enamel knot Present 1N/O , 1M

Specimen 2A/B: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: tertiary enamel knot Present 2A/B


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory