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Gene Expression Data
Assay Details
Assay
Reference: J:191212 Benson MD, et al., Ephrin-B stimulation of calvarial bone formation. Dev Dyn. 2012 Dec;241(12):1901-10
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5586501
Gene symbol: Efnb2
Gene name: ephrin B2
Reporter: lacZ
Direct Detection
Results
Specimen 1B: embryonic day 15.5; Efnb2tm1Henk/Efnb2+ (more )
Structure Level Pattern Image Note
TS23: chondrocranium Present 1B Expressed in the periosteum of the calvaria.
TS23: brain dura mater Strong 1B Expressed in the potently osteogenic dura mater that underlies the calvaria.

Specimen 1C: postnatal day 0; Efnb2tm1Henk/Efnb2+ (more )
Structure Level Pattern Image Note
TS27: chondrocranium Present Regionally restricted 1C Expressed on both the periosteal and endosteal surfaces, at much reduced levels compared to E15.5. Expression was strongest in suture mesenchyme and adjacent bone fronts of both overlapping and abutting sutures.
TS27: cranial suture Present Regionally restricted 1C Expression was strongest in suture mesenchyme and adjacent bone fronts of both overlapping and abutting sutures.

Specimen 1D: postnatal day 0; Efnb2tm1Henk/Efnb2+ (more )
Structure Level Pattern Image Note
TS27: chondrocranium Present Regionally restricted 1D Expressed on both the periosteal and endosteal surfaces, at much reduced levels compared to E15.5. Expression was strongest in suture mesenchyme and adjacent bone fronts of both overlapping and abutting sutures.
TS27: cranial suture Present Regionally restricted 1D Expression was strongest in suture mesenchyme and adjacent bone fronts of both overlapping and abutting sutures.

Specimen 1E: postnatal week 8-12; Efnb2tm1Henk/Efnb2+ (more )
Structure Level Pattern Image Note
TS28: cranial suture Weak Regionally restricted 1E Faint expression in the sutural mesenchyme.
TS28: bone marrow Present Single cells 1E Expressed in a few cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory