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Gene Expression Data
Assay Details
Assay
Reference: J:172277 Mohri Y, et al., Lgr4-deficient mice showed premature differentiation of ureteric bud with reduced expression of Wnt effector Lef1 and Gata3. Dev Dyn. 2011 Jun;240(6):1626-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5585289
Gene symbol: Lef1
Gene name: lymphoid enhancer binding factor 1
Antibody: anti-Lef1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 5G: embryonic day 15.5 (more )
Note: The inset is a higher magnification of the outlined area.
Structure Level Pattern Image Note
TS23: ureteric tip Present 5G
TS23: renal tubule Present Regionally restricted 5G Expression is in the tubule progenitor epithelium.
TS23: renal cortex Present Regionally restricted 5G Expression is in renal vesicles.
Specimen 5H: embryonic day 15.5; Lgr4tm1.2Knis/Lgr4tm1.2Knis (more )
Note: The inset is a higher magnification of the outlined area.
Structure Level Pattern Image Note
TS23: ureteric tip Weak 5H
TS23: renal cortex Present 5H Expression in the tubule progenitor epithelium and renal vesicles is the same as in wild-type embryos.
TS23: renal tubule Present 5H Expression in the tubule progenitor epithelium and renal vesicles is the same as in wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory