Th Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:137167 Tennese AA, et al., Loss of the Prader-Willi syndrome protein necdin causes defective migration, axonal outgrowth, and survival of embryonic sympathetic neurons. Dev Dyn. 2008 Jul;237(7):1935-43
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:5582738
Gene symbol:	Th
Gene name:	tyrosine hydroxylase

Antibody:	anti-Tyrosine hydroxylase (rabbit)
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

2D ©

Specimen 2D: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: superior cervical ganglion	Present		2D

2D' ©

Specimen 2D': embryonic day 14.5; Ndn^tm2Stw/Ndn^tm2Stw (more

)

Structure	Level	Pattern	Image	Note
TS22: superior cervical ganglion	Present		2D'	Expression is similar in the mis-shapen ganglia.

4B ©

Specimen 4B: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: nose	Present	Regionally restricted	4B	Expression is in nerves.
TS26: sympathetic nervous system	Present	Regionally restricted	4B	Expression is in nerves.

4B' ©

Specimen 4B': embryonic day 18.5; Ndn^tm2Stw/Ndn^tm2Stw (more

)

Structure	Level	Pattern	Image	Note
TS26: nose	Weak	Regionally restricted	4B'	Innervation is reduced in this mutant.
TS26: sympathetic nervous system	Weak	Regionally restricted	4B'	Innervation is reduced in this mutant.

4C ©

Specimen 4C: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: submandibular gland	Present	Regionally restricted	4C	Expression is in nerves.
TS26: sympathetic nervous system	Present	Regionally restricted	4C	Expression is in nerves.

4C' ©

Specimen 4C': embryonic day 18.5; Ndn^tm2Stw/Ndn^tm2Stw (more

)

Structure	Level	Pattern	Image	Note
TS26: submandibular gland	Weak	Regionally restricted	4C'	Innervation is reduced in this mutant.
TS26: sympathetic nervous system	Weak	Regionally restricted	4C'	Innervation is reduced in this mutant.

4D ©

Specimen 4D: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: parotid gland	Present	Regionally restricted	4D	Expression is in nerves.
TS26: sympathetic nervous system	Present	Regionally restricted	4D	Expression is in nerves.

4D' ©

Specimen 4D': embryonic day 18.5; Ndn^tm2Stw/Ndn^tm2Stw (more

)

Structure	Level	Pattern	Image	Note
TS26: parotid gland	Weak	Regionally restricted	4D'	Innervation is reduced in this mutant.
TS26: sympathetic nervous system	Weak	Regionally restricted	4D'	Innervation is reduced in this mutant.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24