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Gene Expression Data
Assay Details
Assay
Reference: J:174611 Azhar M, et al., Transforming growth factor Beta2 is required for valve remodeling during heart development. Dev Dyn. 2011 Sep;240(9):2127-41
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5576195
Gene symbol: Smad3
Gene name: SMAD family member 3
Antibody: phospho-SMAD2/3
Assay notes: This antibody detects the phosphorylated form of the protein.
Results
Specimen 6A: embryonic day 18.5 (more )
Note: Boxes in A are magnified in D and F.
Structure Level Pattern Image Note
TS26: mitral valve Present 6D , 6A
TS26: tricuspid valve Present 6F , 6A
Specimen 6B: embryonic day 18.5; Tgfb2tm1Doe/Tgfb2tm1Doe (more )
Note: Boxes in B are magnified in E and G.
Structure Level Pattern Image Note
TS26: mitral valve Present 6B , 6E The number of positive cells decreased from 95.8% to 72.0% in this mutant.
TS26: tricuspid valve Present 6B , 6G The number of positive cells decreased from 95.8% to 72.0% in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory