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Gene Expression Data
Assay Details
Assay
Reference: J:156926 Hayashi T, et al., Expression patterns of FGF receptors in the developing mammalian cochlea. Dev Dyn. 2010 Feb 3;239(3):1019-1026
Assay type: RNA in situ
MGI Accession ID: MGI:5571866
Gene symbol: Fgfr1
Gene name: fibroblast growth factor receptor 1
Probe: Fgfr1 cDNA19
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: This probe detects both splice forms of the receptor.
Results
Specimen 1A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cochlear duct epithelium Present Diffuse 1A
TS21: cochlear duct mesenchyme Present Diffuse 1A

Specimen 1E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlear duct epithelium Present Regionally restricted 1E Expression is highest in the ventral aspect of the duct.
TS22: cochlear duct mesenchyme Present Regionally restricted 1E Expression is highest in the ventral aspect of the duct.

Specimen 1I: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cochlear duct Present Regionally restricted 1I Expression is highest in the ventral aspect of the duct. Toward the base of the cochlea expression is concentrated in a cluster of cells at the lateral aspect of the prosensory domain in the region of the developing outer hair cells.

Specimen 3B: embryonic day 15.5 (more )
Note: B' is a higher magnification image of the basal turn shown boxed in B.
Structure Level Pattern Image Note
TS23: cochlear duct Present 3B' , 3B Expression is highest in the ventral aspect of the duct.

Specimen 4A: embryonic day 15.0 (more )
Note: The mid-basal turn (turn 2) is shown in A'.
Structure Level Pattern Image Note
TS23: cochlear duct Present Regionally restricted 4A' , 4A Expression is highest in the ventral aspect of the duct.

Specimen 4D: embryonic day 15.0 (more )
Note: Pseudocolored combinations to show the relationship among the expression patterns.
Structure Level Pattern Image Note
TS23: cochlear duct Present Regionally restricted 4D Expression is highest in the ventral aspect of the duct.

Specimen 4F: embryonic day 15.0 (more )
Note: Pseudocolored combinations to show the relationship among the expression patterns.
Structure Level Pattern Image Note
TS23: cochlear duct Present Regionally restricted 4F Expression is highest in the ventral aspect of the duct.

Specimen 5A: embryonic day 16.5 (more )
Note: The basal turn (turn 1) is shown in A'.
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 5A' , 5A Expression is highest in the cells in the lateral part of the prosensory domain.
TS24: cochlear duct epithelium Present 5A' , 5A

Specimen 5E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cochlea Present Regionally restricted 5E Weak expression in the sensory region.
TS26: greater epithelial ridge Present 5E
TS26: cochlea epithelium Present 5E

Specimen 6A: postnatal day 0 (more )
Note: The basal turn (turn 1) is shown in A'.
Structure Level Pattern Image Note
TS27: cochlear duct Present Regionally restricted 6A , 6A' Expression is at the lateral edge of the sensory epithelium in Hensen's cells and is nearly absent in the sensory domain.
TS27: spiral sulcus Present 6A' , 6A

Specimen 7A: postnatal day 3 (more )
Note: The basal turn (turn 1) is shown in A'.
Structure Level Pattern Image Note
TS27: cochlear duct Present Regionally restricted 7A , 7A' Expression is at the lateral edge of the sensory epithelium in Hensen's cells and is nearly absent in the sensory domain.

Specimen S1A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lateral ventricle Strong S1A
TS21: cochlear duct epithelium Present Diffuse S1A
TS21: cochlear duct mesenchyme Present Diffuse S1A


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory