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Gene Expression Data
Assay Details
Assay
Reference: J:108819 Miyoshi T, et al., Complementary expression pattern of Zfhx1 genes Sip1 and deltaEF1 in the mouse embryo and their genetic interaction revealed by compound mutants. Dev Dyn. 2006 Apr 5;235(7):1941-1952
Assay type: RNA in situ
MGI Accession ID: MGI:5550537
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Probe: Sox2 probe5
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4Ea: embryonic day 8.5 (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present 4Ea

Specimen 4Eb: embryonic day 8.5; Zeb1tm2Yhi/Zeb1tm2Yhi (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present 4Eb Comparable to that in wild-type.

Specimen 4Ec: embryonic day 8.5; Zeb2tm1.2Yhi/Zeb2tm1.2Yhi (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present Regionally restricted 4Ec Significantly decreased expression throughout the neural plate. Significant expression levels were retained in the anterior area, in a rhombomeric region (comprising r3 and a slightly more posterior region), and in the nascent posterior neural plate.
TS13: rhombomere 3 Present 4Ec

Specimen 4Ed: embryonic day 8.5; Zeb1tm2Yhi/Zeb1tm2Yhi, Zeb2tm1.2Yhi/Zeb2tm1.2Yhi (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present Regionally restricted 4Ed More severely decreased expression throughout the neural plate. Significant expression levels were retained only in the anterior area.

Specimen 4Ee: embryonic day 8.5 (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present 4Ee

Specimen 4Ef: embryonic day 8.5; Zeb1tm2Yhi/Zeb1tm2Yhi (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present 4Ef

Specimen 4Eg: embryonic day 8.5; Zeb2tm1.2Yhi/Zeb2tm1.2Yhi (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present Regionally restricted 4Eg Significantly decreased expression throughout the neural plate. Significant expression levels were retained in the anterior area, in a rhombomeric region (comprising r3 and a slightly more posterior region), and in the nascent posterior neural plate.

Specimen 4Eh: embryonic day 8.5; Zeb1tm2Yhi/Zeb1tm2Yhi, Zeb2tm1.2Yhi/Zeb2tm1.2Yhi (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present Regionally restricted 4Eh More severely decreased expression throughout the neural plate. Significant expression levels were retained only in the anterior area.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory