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Gene Expression Data
Assay Details
Assay
Reference: J:119850 Oh S, et al., Specific requirements of sonic hedgehog signaling during oligodendrocyte development. Dev Dyn. 2005 Nov;234(3):489-96
Assay type: RNA in situ
MGI Accession ID: MGI:5544945
Gene symbol: Olig2
Gene name: oligodendrocyte transcription factor 2
Probe: Olig2 probe10
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 1A Expression was restricted to a discrete domain near the floor plate of the ventral neural tube.
Specimen 1C: embryonic day 12.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 1C Expression was localized similar to wild type but there was a moderate reduction in the expression level.
Specimen 1D: embryonic day 12.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 1D Expression was comparable between wild type and mutant.
Specimen 1E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: spinal cord Present Regionally restricted 1E Expressing cells began to populate the spinal cord outside of the ventricular zone.
Specimen 1G: embryonic day 13.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS21: spinal cord ventricular layer Present 1G Expression in the mutant was still largely restricted to the ventricular zone.
Specimen 1H: embryonic day 13.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS21: spinal cord Present Regionally restricted 1H Expression was comparable between wild type and mutant.
Specimen 1I: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord Present Widespread 1I Expressing cells were dispersed throughout the spinal cord.
Specimen 1K: embryonic day 14.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS22: spinal cord Present Widespread 1K Expressing cells were dispersed throughout the spinal cord as in wild type.
Specimen 1L: embryonic day 14.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS22: spinal cord Present Regionally restricted 1L Expression was comparable between wild type and mutant.
Specimen 4I left: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 4I left Expression was detected in the ventral progenitor domain.
Specimen 4J left: embryonic day 11.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 4J left Expression was detected in the ventral progenitor domain.
Specimen 4K left: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 4K left Expression was detected in the ventral progenitor domain.
Specimen 4L left: embryonic day 12.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 4L left Expression was detected in the ventral progenitor domain.
Specimen 4M left: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: spinal cord Present Regionally restricted 4M left Expression was detected in the ventral progenitor domain.
Specimen 4N left: embryonic day 13.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS21: spinal cord Present Regionally restricted 4N left Expression was detected in the ventral progenitor domain.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory