Gene Expression Data
Assay Details
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Assay
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Reference:
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J:100234
Shao Y, et al., Expression of voltage sensitive calcium channel (VSCC) L-type Cav1.2 (alpha1C) and T-type Cav3.2 (alpha1H) subunits during mouse bone development. Dev Dyn. 2005 Sep;234(1):54-62
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5544807
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Gene symbol:
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Cacna1c
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Gene name:
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calcium channel, voltage-dependent, L type, alpha 1C subunit
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Results
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Specimen
1D:
embryonic day 14.5
(more  )
Specimen
1D:
(close  )
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Genetic Background:
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involves: FVB/N * Swiss Webster
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: femur cartilage condensation |
Strong |
Regionally restricted |
1D
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Expression is along the perichondrium, with additional staining in the proliferative chondrocytic regions of the non-mineralized cartilage at the growth plates.
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Specimen
1E:
embryonic day 16.5
(more )
Specimen
1E:
(close )
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Genetic Background:
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involves: FVB/N * Swiss Webster
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: femur |
Strong |
Regionally restricted |
1E
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Expression is in regions of rapid growth of long bone, including the perichondrium, periosteum, chondro-osseous junction, and along the surfaces of newly formed trabecular bone.
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Specimen
1F:
embryonic day 18.5
(more )
Specimen
1F:
(close )
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Genetic Background:
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involves: FVB/N * Swiss Webster
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: femur |
Strong |
Regionally restricted |
1F
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Expression is in regions of rapid growth of long bone, including the perichondrium, periosteum, chondro-osseous junction, and along the surfaces of newly formed trabecular bone.
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Specimen
not shown:
postnatal newborn
(more )
Specimen
not shown:
(close )
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Genetic Background:
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involves: FVB/N * Swiss Webster
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: femur |
Present |
Regionally restricted |
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Expression is in regions of rapid growth of long bone, including the perichondrium, periosteum, chondro-osseous junction, and along the surfaces of newly formed trabecular bone.
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Specimen
2A,D:
embryonic day 18.5
(more )
Specimen
2A,D:
(close )
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Genetic Background:
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involves: FVB/N * Swiss Webster
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: femur |
Strong |
Regionally restricted |
2D
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2A
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Expression is in osteoblasts and in chondrocytes located in the hypertrophic zone.
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Specimen
2B,E:
embryonic day 18.5
(more )
Specimen
2B,E:
(close )
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Genetic Background:
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involves: FVB/N * Swiss Webster
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: femur |
Strong |
Regionally restricted |
2E
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2B
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Expression is in the periosteum.
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Specimen
2C,F:
embryonic day 18.5
(more )
Specimen
2C,F:
(close )
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Genetic Background:
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involves: FVB/N * Swiss Webster
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: femur |
Strong |
Regionally restricted |
2F
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2C
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Expression is in the perichondrium.
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Specimen
3A,D:
postnatal week 6
(more )
Specimen
3A,D:
(close )
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Genetic Background:
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involves: FVB/N * Swiss Webster
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: femur |
Strong |
Regionally restricted |
3D
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3A
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Expression is in the osteoblasts lining the surfaces of spongy bone and in bone marrow stromal cells, absent in post-mitotic osteocytes.
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Analysis Tools