Hdc RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type:	RNA in situ
MGI Accession ID:	MGI:5542034
Gene symbol:	Hdc
Gene name:	histidine decarboxylase

Probe:	RIKEN clone E430019O14 subclone
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

GUDMAP:9163 ©

Specimen GUDMAP:9163: postnatal adult (more

)
Note: This animal was sexually mature. Labeling was visualized using BM purple.

Structure	Level	Image
TS28: urinary system	Present	GUDMAP:9163
TS28: metanephros	Present	GUDMAP:9163
TS28: renal cortex	Present	GUDMAP:9163
TS28: cortical renal tubule	Present	GUDMAP:9163
TS28: renal proximal tubule	Present	GUDMAP:9163
TS28: renal proximal convoluted tubule	Present	GUDMAP:9163
TS28: segment 1 of proximal tubule	Present	GUDMAP:9163
TS28: segment 2 of proximal tubule	Present	GUDMAP:9163
TS28: mature renal corpuscle	Absent	GUDMAP:9163
TS28: glomerular tuft	Absent	GUDMAP:9163
TS28: glomerular capillary system	Absent	GUDMAP:9163
TS28: glomerular mesangium of glomerular tuft	Absent	GUDMAP:9163
TS28: glomerular basement membrane of mature renal corpuscle	Absent	GUDMAP:9163
TS28: visceral epithelium of mature renal corpuscle	Absent	GUDMAP:9163
TS28: Bowman's capsule of mature renal corpuscle	Absent	GUDMAP:9163
TS28: parietal epithelium of mature renal corpuscle	Absent	GUDMAP:9163
TS28: urinary space of mature renal corpuscle	Absent	GUDMAP:9163
TS28: proximal straight tubule of outer stripe of outer medulla	Absent	GUDMAP:9163

GUDMAP:9164 ©

Specimen GUDMAP:9164: embryonic day 15.5 (more

)
Note: Labeling was visualized using BM purple.

Structure	Level	Pattern	Image	Note
TS23: urinary system	Present	Regionally restricted	GUDMAP:9164
TS23: metanephros	Present	Regionally restricted	GUDMAP:9164
TS23: renal cortex	Present	Regionally restricted	GUDMAP:9164
TS23: cortical renal tubule	Present	Regionally restricted	GUDMAP:9164	graded expression; strong expression in subset of tubules including early proximal and possibly distal
TS23: cortical early proximal tubule	Present	Regionally restricted	GUDMAP:9164	expression detected in the S1 segment adjacent to the renal corpuscle of maturing nephrons at the urinary pole. Expression absent from early proximal tubules of capillary loop nephrons
TS23: renal medulla	Present	Regionally restricted	GUDMAP:9164
TS23: immature loop of Henle	Present	Regionally restricted	GUDMAP:9164	weak to moderate expression in a subset of loop of Henle
TS23: maturing nephron	Present	Regionally restricted	GUDMAP:9164
TS23: late tubule	Present	Regionally restricted	GUDMAP:9164
TS23: cortical early distal tubule	Present	Regionally restricted	GUDMAP:9164	weaker expression detected in capillary loop nephrons and possible strong expression in maturing nephrons however the early distal tubules of maturing nephrons are difficult to identify
TS23: renal capsule	Absent		GUDMAP:9164
TS23: nephrogenic zone	Absent		GUDMAP:9164
TS23: nephrogenic interstitium	Absent		GUDMAP:9164
TS23: cap mesenchyme	Absent		GUDMAP:9164
TS23: pretubular aggregate	Absent		GUDMAP:9164
TS23: ureteric tip	Absent		GUDMAP:9164
TS23: ureteric tree terminal branch excluding tip itself	Absent		GUDMAP:9164
TS23: renal vesicle	Absent		GUDMAP:9164
TS23: comma-shaped body	Absent		GUDMAP:9164
TS23: upper limb of comma-shaped body	Absent		GUDMAP:9164
TS23: lower limb of comma-shaped body	Absent		GUDMAP:9164
TS23: s-shaped body	Absent		GUDMAP:9164
TS23: renal connecting tubule of s-shaped body	Absent		GUDMAP:9164
TS23: distal segment of s-shaped body	Absent		GUDMAP:9164
TS23: medial segment of s-shaped body	Absent		GUDMAP:9164
TS23: proximal segment of s-shaped body	Absent		GUDMAP:9164
TS23: visceral epithelium of s-shaped body	Absent		GUDMAP:9164
TS23: parietal epithelium of s-shaped body	Absent		GUDMAP:9164
TS23: renal medullary interstitium	Absent		GUDMAP:9164
TS23: renal medullary vasculature	Absent		GUDMAP:9164
TS23: renal medullary arterial system	Absent		GUDMAP:9164
TS23: renal medullary venous system	Absent		GUDMAP:9164
TS23: renal medullary capillary	Absent		GUDMAP:9164
TS23: medullary collecting duct	Absent		GUDMAP:9164
TS23: renal pelvis	Absent		GUDMAP:9164
TS23: pelvic urothelial lining	Absent		GUDMAP:9164
TS23: pelvic smooth muscle	Absent		GUDMAP:9164
TS23: perihilar interstitium	Absent		GUDMAP:9164
TS23: capillary loop renal corpuscle	Absent		GUDMAP:9164
TS23: visceral epithelium of capillary loop renal corpuscle	Absent		GUDMAP:9164
TS23: parietal epithelium of capillary loop renal corpuscle	Absent		GUDMAP:9164
TS23: presumptive mesangium of capillary loop renal corpuscle	Absent		GUDMAP:9164
TS23: presumptive endothelium of capillary loop renal corpuscle	Absent		GUDMAP:9164
TS23: associated interstitium of capillary loop renal corpuscle	Absent		GUDMAP:9164
TS23: maturing renal corpuscle	Absent		GUDMAP:9164
TS23: maturing glomerular tuft	Absent		GUDMAP:9164
TS23: glomerular capillary system of maturing glomerular tuft	Absent		GUDMAP:9164
TS23: glomerular basement membrane of maturing renal corpuscle	Absent		GUDMAP:9164
TS23: glomerular mesangium of maturing glomerular tuft	Absent		GUDMAP:9164
TS23: visceral epithelium of maturing renal corpuscle	Absent		GUDMAP:9164
TS23: Bowman's capsule of maturing renal corpuscle	Absent		GUDMAP:9164
TS23: parietal epithelium of maturing renal corpuscle	Absent		GUDMAP:9164
TS23: glomerular mesangium of maturing renal corpuscle	Absent		GUDMAP:9164
TS23: juxtaglomerular arteriole	Absent		GUDMAP:9164
TS23: cortical collecting duct	Absent		GUDMAP:9164
TS23: renal cortical interstitium	Absent		GUDMAP:9164
TS23: renal cortical vasculature	Absent		GUDMAP:9164
TS23: renal cortical arterial system	Absent		GUDMAP:9164
TS23: renal cortical venous system	Absent		GUDMAP:9164
TS23: renal cortical capillary	Absent		GUDMAP:9164
TS23: developing capillary loop stage nephron group	Absent		GUDMAP:9164
TS23: collecting duct	Absent		GUDMAP:9164
TS23: renal interstitium	Absent		GUDMAP:9164
TS23: renal vasculature	Absent		GUDMAP:9164
TS23: early nephron	Absent		GUDMAP:9164
TS23: renal connecting tubule	Absent		GUDMAP:9164
TS23: anlage of loop of Henle of cortical renal tubule	Absent		GUDMAP:9164
TS23: cortical renal tubule of maturing nephron group	Present	Regionally restricted	GUDMAP:9164
TS23: early proximal tubule of maturing nephron	Present		GUDMAP:9164
TS23: early distal tubule of capillary loop nephron	Present		GUDMAP:9164
TS23: renal connecting tubule of maturing nephron	Absent		GUDMAP:9164
TS23: early proximal tubule of capillary loop nephron	Absent		GUDMAP:9164
TS23: early distal tubule of maturing nephron	Ambiguous		GUDMAP:9164	possible strong expression in maturing nephrons however the early distal tubules of maturing nephrons are difficult to identify

GUDMAP:9165 ©

Specimen GUDMAP:9165: embryonic day 15.5 (more

)
Note: Labeling was visualized using BM purple.

Structure	Level	Image
TS23: ureter	Absent	GUDMAP:9165
TS23: urothelium of ureter	Absent	GUDMAP:9165
TS23: superficial cell layer of ureter	Absent	GUDMAP:9165
TS23: intermediate cell layer of ureter	Absent	GUDMAP:9165
TS23: basal cell layer of ureter	Absent	GUDMAP:9165
TS23: ureteral mesenchyme	Absent	GUDMAP:9165
TS23: ureteral mesenchyme subepithelial layer	Absent	GUDMAP:9165
TS23: ureteral smooth muscle layer	Absent	GUDMAP:9165
TS23: ureteral smooth muscle layer smooth muscle component	Absent	GUDMAP:9165
TS23: ureteral smooth muscle layer interstitium	Absent	GUDMAP:9165
TS23: ureteral mesenchyme outer layer	Absent	GUDMAP:9165
TS23: ureteral vasculature	Absent	GUDMAP:9165

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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