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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5541821
Gene symbol: Tcf21
Gene name: transcription factor 21
Probe: RIKEN clone 2610027O10 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:13432: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: urinary system Present GUDMAP:13432
TS23: metanephros Present GUDMAP:13432
TS23: nephrogenic zone Present GUDMAP:13432
TS23: nephrogenic interstitium Present Regionally restricted GUDMAP:13432 Expression detected in a subset of the nephrogenic interstitium (uninduced stroma). Expression is detected adjacent to the cortex and absent from the outer surface of the metanephros. Expression is detected at the top of T-shaped ureteric tips adjacent to the cap mesenchyme.
TS23: renal cortex Present GUDMAP:13432
TS23: renal cortical interstitium Present GUDMAP:13432
TS23: cap mesenchyme Absent GUDMAP:13432
TS23: ureteric tip Absent GUDMAP:13432
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:13432
TS23: renal vesicle Absent GUDMAP:13432
TS23: comma-shaped body Present GUDMAP:13432
TS23: cortical renal tubule Absent GUDMAP:13432
TS23: cortical collecting duct Absent GUDMAP:13432
TS23: renal cortical vasculature Absent GUDMAP:13432
TS23: immature loop of Henle Absent GUDMAP:13432
TS23: medullary collecting duct Absent GUDMAP:13432
TS23: s-shaped body Present GUDMAP:13432
TS23: proximal segment of s-shaped body Present GUDMAP:13432
TS23: capillary loop renal corpuscle Present GUDMAP:13432
TS23: visceral epithelium of capillary loop renal corpuscle Present GUDMAP:13432
TS23: maturing renal corpuscle Present GUDMAP:13432
TS23: maturing glomerular tuft Present GUDMAP:13432
TS23: visceral epithelium of maturing renal corpuscle Present GUDMAP:13432
TS23: medial segment of s-shaped body Absent GUDMAP:13432
TS23: distal segment of s-shaped body Absent GUDMAP:13432
TS23: renal connecting tubule of s-shaped body Absent GUDMAP:13432
TS23: associated interstitium of capillary loop renal corpuscle Absent GUDMAP:13432
TS23: parietal epithelium of capillary loop renal corpuscle Absent GUDMAP:13432
TS23: presumptive endothelium of capillary loop renal corpuscle Absent GUDMAP:13432
TS23: presumptive mesangium of capillary loop renal corpuscle Absent GUDMAP:13432
TS23: glomerular capillary system of maturing glomerular tuft Absent GUDMAP:13432
TS23: glomerular mesangium of maturing glomerular tuft Absent GUDMAP:13432
TS23: glomerular basement membrane of maturing renal corpuscle Absent GUDMAP:13432
TS23: Bowman's capsule of maturing renal corpuscle Absent GUDMAP:13432
TS23: juxtaglomerular arteriole Absent GUDMAP:13432
TS23: lower limb of comma-shaped body Present GUDMAP:13432
TS23: upper limb of comma-shaped body Absent GUDMAP:13432
TS23: renal connecting segment of comma-shaped body Absent GUDMAP:13432
TS23: early tubule Present GUDMAP:13432
TS23: developing capillary loop stage nephron group Present GUDMAP:13432
TS23: maturing nephron Present GUDMAP:13432
TS23: late tubule Present GUDMAP:13432
TS23: renal medulla Present GUDMAP:13432
TS23: renal medullary interstitium Present GUDMAP:13432
TS23: renal pelvis Present GUDMAP:13432
TS23: perihilar interstitium Ambiguous GUDMAP:13432 Possible weak expression in the perihilar interstitium, but strongest expression is detected in the pelvic and ureteral smooth muscle layers.
TS23: pelvic smooth muscle Present GUDMAP:13432
TS23: pelvic urothelial lining Absent GUDMAP:13432
TS23: collecting duct Absent GUDMAP:13432
TS23: ureteric trunk Absent GUDMAP:13432
TS23: renal interstitium Present GUDMAP:13432
Specimen GUDMAP:13433: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: urinary system Present GUDMAP:13433
TS23: metanephros Present GUDMAP:13433
TS23: renal pelvis Present GUDMAP:13433
TS23: pelvic smooth muscle Present GUDMAP:13433
TS23: ureter Present GUDMAP:13433
TS23: ureteral mesenchyme Present GUDMAP:13433
TS23: ureteral smooth muscle layer Present GUDMAP:13433
TS23: pelvic urothelial lining Absent GUDMAP:13433
TS23: urothelium of ureter Absent GUDMAP:13433
TS23: ureteral mesenchyme outer layer Absent GUDMAP:13433
TS23: perihilar interstitium Ambiguous GUDMAP:13433 Possible weak expression in the perihilar interstitium, however strongest expression is detected in the pelvic smooth muscle layer.
TS23: ureteral mesenchyme subepithelial layer Ambiguous GUDMAP:13433
TS23: ureteral smooth muscle layer smooth muscle component Present GUDMAP:13433
TS23: ureteral smooth muscle layer interstitium Present GUDMAP:13433
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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