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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5540878
Gene symbol: Ptn
Gene name: pleiotrophin
Probe: RIKEN clone 2610008G07 subclone 1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:7638: embryonic day 12.5 (more )
Note: This specimen was generated and annotated by the lab of Melissa H. Little, Murdoch Children's Research Institute. Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: urinary system Present Regionally restricted GUDMAP:7638
TS20: urogenital mesentery Present GUDMAP:7638
TS20: metanephros Absent GUDMAP:7638
Specimen GUDMAP:7639: embryonic day 12.5 (more )
Note: This specimen was generated and annotated by the lab of Melissa H. Little, Murdoch Children's Research Institute. Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: female reproductive system Present GUDMAP:7639
TS20: mesonephros of female Present Regionally restricted GUDMAP:7639 graded expression
TS20: mesonephric mesenchyme of female Present GUDMAP:7639 graded signal strongest adjacent to ovary; no signal surrounding the paramesonephric duct of female mesonephric portion
TS20: urogenital mesentery Present GUDMAP:7639
TS20: ovary Absent GUDMAP:7639
TS20: paramesonephric duct of female, mesonephric portion Absent GUDMAP:7639
TS20: paramesonephric duct of female, rest of Absent GUDMAP:7639
TS20: nephric duct, metanephric portion Absent GUDMAP:7639
TS20: mesonephric tubule of female Absent GUDMAP:7639
Specimen GUDMAP:7640: embryonic day 10.5 (more )
Note: This specimen was generated and annotated by the lab of Melissa H. Little, Murdoch Children's Research Institute. Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS17: genitourinary system Present GUDMAP:7640
TS17: mesonephros Present GUDMAP:7640
TS17: mesonephros mesenchyme Present GUDMAP:7640
TS17: cloaca Present GUDMAP:7640
TS17: genitourinary system mesenchyme Present GUDMAP:7640
TS17: metanephric mesenchyme Absent GUDMAP:7640
TS17: nephric duct, metanephric portion Absent GUDMAP:7640
TS17: nephric duct, mesonephric portion Absent GUDMAP:7640
TS17: gonad primordium Absent GUDMAP:7640
Specimen GUDMAP:7641: embryonic day 12.5 (more )
Note: This specimen was generated and annotated by the lab of Melissa H. Little, Murdoch Children's Research Institute. Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: male reproductive system Present GUDMAP:7641
TS20: mesonephros of male Present Regionally restricted GUDMAP:7641 graded expression
TS20: mesonephric mesenchyme of male Present GUDMAP:7641 graded signal strongest adjacent to testis; no signal surrounding the paramesonephric duct of male mesonephric portion
TS20: urogenital mesentery Present GUDMAP:7641
TS20: testis Absent GUDMAP:7641
TS20: paramesonephric duct of male, mesonephric portion Absent GUDMAP:7641
TS20: nephric duct, metanephric portion Absent GUDMAP:7641
TS20: paramesonephric duct of male, rest of Absent GUDMAP:7641
TS20: mesonephric tubule of male Absent GUDMAP:7641
Specimen GUDMAP:7650: embryonic day 15.5 (more )
Note: This specimen was generated and annotated by the lab of Melissa H. Little, Murdoch Children's Research Institute. This assay's probe was visualized using NBT/BCIP (blue). This section was which also subjected to immunohistochemistry with an anti-Wt1 antibody visualized with DAB (orange).
Structure Level Pattern Image Note
TS23: urinary system Present GUDMAP:7650
TS23: metanephros Present Regionally restricted GUDMAP:7650
TS23: nephrogenic zone Present GUDMAP:7650
TS23: nephrogenic interstitium Present GUDMAP:7650
TS23: ureteric tip Present GUDMAP:7650
TS23: cap mesenchyme Present GUDMAP:7650
TS23: renal cortex Present GUDMAP:7650
TS23: renal cortical interstitium Present GUDMAP:7650 expression in a subset of the cortical interstitium strongest closest to the nephrogenic zone but weaker within the nephrogenic interstitium then weaker expression in the remainder of the cortical interstitium
TS23: comma-shaped body Present GUDMAP:7650
TS23: lower limb of comma-shaped body Present GUDMAP:7650
TS23: s-shaped body Present GUDMAP:7650
TS23: distal segment of s-shaped body Present GUDMAP:7650
TS23: proximal segment of s-shaped body Present GUDMAP:7650
TS23: capillary loop renal corpuscle Present GUDMAP:7650
TS23: presumptive mesangium of capillary loop renal corpuscle Present GUDMAP:7650
TS23: associated interstitium of capillary loop renal corpuscle Present GUDMAP:7650
TS23: maturing renal corpuscle Present GUDMAP:7650
TS23: maturing glomerular tuft Present GUDMAP:7650
TS23: glomerular mesangium of maturing glomerular tuft Present GUDMAP:7650
TS23: cortical renal tubule Present GUDMAP:7650 subset of cortical renal tubule s
TS23: cortical early distal tubule Present GUDMAP:7650
TS23: renal medulla Present GUDMAP:7650
TS23: immature loop of Henle Present GUDMAP:7650
TS23: renal pelvis Present GUDMAP:7650
TS23: perihilar interstitium Present GUDMAP:7650
TS23: ureter Present GUDMAP:7650
TS23: ureteral mesenchyme Present GUDMAP:7650
TS23: ureteral mesenchyme outer layer Present GUDMAP:7650
TS23: cortical collecting duct Absent GUDMAP:7650
TS23: medullary collecting duct Absent GUDMAP:7650
TS23: upper limb of comma-shaped body Absent GUDMAP:7650
TS23: renal medullary interstitium Absent GUDMAP:7650
TS23: glomerular mesangium of maturing renal corpuscle Ambiguous GUDMAP:7650
TS23: pelvic smooth muscle Ambiguous GUDMAP:7650
Specimen GUDMAP:8210: embryonic day 15.5 (more )
Note: This specimen was generated and annotated by the lab of Melissa H. Little, Murdoch Children's Research Institute. This assay's probe was visualized using NBT/BCIP (blue). This section was which also subjected to immunohistochemistry with an anti-Wt1 antibody visualized with DAB (orange).
Structure Level Pattern Image Note
TS23: urinary system Present GUDMAP:8210
TS23: metanephros Present GUDMAP:8210
TS23: nephrogenic zone Present GUDMAP:8210
TS23: nephrogenic interstitium Present GUDMAP:8210
TS23: ureteric tip Present GUDMAP:8210 weak signal
TS23: cap mesenchyme Present GUDMAP:8210 weak signal
TS23: renal cortex Present GUDMAP:8210
TS23: renal cortical interstitium Present GUDMAP:8210 expression in a subset of the cortical interstitium strongest closest to the nephrogenic zone but weaker within the nephrogenic interstitium then weaker expression in the remainder of the cortical interstitium
TS23: comma-shaped body Present GUDMAP:8210 moderate signal at lower limb of S-shaped body possibly adjacent to parietal and visceral cell layers expressing Wt1 protein
TS23: lower limb of comma-shaped body Present GUDMAP:8210
TS23: s-shaped body Present GUDMAP:8210
TS23: distal segment of s-shaped body Present GUDMAP:8210
TS23: proximal segment of s-shaped body Present GUDMAP:8210
TS23: capillary loop renal corpuscle Present GUDMAP:8210
TS23: presumptive mesangium of capillary loop renal corpuscle Present GUDMAP:8210
TS23: associated interstitium of capillary loop renal corpuscle Present GUDMAP:8210
TS23: maturing renal corpuscle Present GUDMAP:8210
TS23: maturing glomerular tuft Present GUDMAP:8210
TS23: glomerular mesangium of maturing glomerular tuft Present GUDMAP:8210
TS23: cortical renal tubule Present GUDMAP:8210 subset of cortical renal tubule show moderate expression most likely early distal tubule
TS23: cortical early distal tubule Present GUDMAP:8210
TS23: renal medulla Present GUDMAP:8210
TS23: immature loop of Henle Present GUDMAP:8210
TS23: renal pelvis Present GUDMAP:8210
TS23: perihilar interstitium Present GUDMAP:8210
TS23: ureter Present GUDMAP:8210
TS23: ureteral mesenchyme Present GUDMAP:8210
TS23: ureteral mesenchyme outer layer Present GUDMAP:8210
TS23: cortical collecting duct Absent GUDMAP:8210
TS23: medullary collecting duct Absent GUDMAP:8210
TS23: upper limb of comma-shaped body Absent GUDMAP:8210
TS23: renal medullary interstitium Absent GUDMAP:8210 expression appears to be absent
TS23: glomerular mesangium of maturing renal corpuscle Ambiguous GUDMAP:8210 either mesangium or adjacent renal cortical interstitium
TS23: pelvic smooth muscle Ambiguous GUDMAP:8210
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
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