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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5540864
Gene symbol: Gria4
Gene name: glutamate receptor, ionotropic, AMPA4 (alpha 4)
Probe: RIKEN clone 9630045B04 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:8917: embryonic day 10.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS17: genitourinary system Ambiguous GUDMAP:8917 signal may be background staining
TS17: genitourinary system mesenchyme Ambiguous GUDMAP:8917
TS17: gonad primordium Ambiguous GUDMAP:8917
TS17: mesonephros Ambiguous GUDMAP:8917
TS17: metanephric mesenchyme Ambiguous GUDMAP:8917
TS17: nephric duct Ambiguous GUDMAP:8917

Specimen GUDMAP:8918: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: male reproductive system Present Regionally restricted GUDMAP:8918
TS21: mesonephros of male Present Regionally restricted GUDMAP:8918
TS21: mesonephric mesenchyme of male Present Regionally restricted GUDMAP:8918 medial and dorsal expression
TS21: testis Present Ubiquitous GUDMAP:8918
TS21: mesonephric tubule of male Ambiguous GUDMAP:8918 possible expression
TS21: nephric duct of male, mesonephric portion Ambiguous GUDMAP:8918 possible expression

Specimen GUDMAP:8919: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: female reproductive system Present Regionally restricted GUDMAP:8919
TS21: mesonephros of female Present Regionally restricted GUDMAP:8919
TS21: mesonephric mesenchyme of female Present Regionally restricted GUDMAP:8919 medial and dorsal expression; signal is absent from the lateral mesenchyme surrounding the nephric and paramesonephric ducts and strongest on the dorsal side of the mesonephros
TS21: mesonephric tubule of female Absent GUDMAP:8919
TS21: nephric duct of female, mesonephric portion Absent GUDMAP:8919
TS21: paramesonephric duct of female, mesonephric portion Absent GUDMAP:8919
TS21: coelomic epithelium of female mesonephros Absent GUDMAP:8919
TS21: nephric duct of female, rest of Absent GUDMAP:8919
TS21: paramesonephric duct of female, rest of Absent GUDMAP:8919
TS21: ovary Ambiguous GUDMAP:8919 possible weak signal

Specimen GUDMAP:8920: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP. Male and female were examined; only the female is shown. Annotators reported the male expression pattern in the metanephros is identical to female.
Structure Level Pattern Image Note
TS21: urinary system Present Regionally restricted GUDMAP:8920
TS21: urogenital mesentery Present GUDMAP:8920
TS21: metanephros Present Regionally restricted GUDMAP:8920
TS21: renal pelvis Present GUDMAP:8920
TS21: ureter Present GUDMAP:8920 signal is either weak or absent from the urothelium layer
TS21: renal capsule Ambiguous GUDMAP:8920 possible expression
TS21: cap mesenchyme Ambiguous GUDMAP:8920 signal is either weak or absent
TS21: ureteric tip Ambiguous GUDMAP:8920 signal is either weak or absent
TS21: early nephron Ambiguous GUDMAP:8920 signal is either weak or absent
TS21: nephrogenic zone Ambiguous GUDMAP:8920
TS21: nephrogenic interstitium Ambiguous GUDMAP:8920
TS21: renal interstitium Present GUDMAP:8920

Specimen GUDMAP:8921: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP. Male and female were examined; only the female is shown. Annotators reported the male expression pattern in the ureter is identical to female.
Structure Level Pattern Image Note
TS21: urinary system Present Regionally restricted GUDMAP:8921
TS21: ureter Present GUDMAP:8921 signal is either weak or absent from the urothelium layer
TS21: urogenital sinus Ambiguous GUDMAP:8921
TS21: primitive bladder Ambiguous GUDMAP:8921 signal seen is likely to be background staining

Specimen GUDMAP:9902: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: urinary system Present GUDMAP:9902
TS23: metanephros Present Regionally restricted GUDMAP:9902
TS23: nephrogenic zone Present Regionally restricted GUDMAP:9902
TS23: nephrogenic interstitium Present GUDMAP:9902 expression weaker than in cortical interstitium.
TS23: renal cortex Present Regionally restricted GUDMAP:9902
TS23: cortical renal tubule Present Regionally restricted GUDMAP:9902 a subset of tubules show expression.
TS23: renal cortical interstitium Present GUDMAP:9902
TS23: renal medulla Present Regionally restricted GUDMAP:9902
TS23: renal medullary interstitium Present GUDMAP:9902 expression in the medullary interstitium is not ubiquitous.
TS23: renal pelvis Present Regionally restricted GUDMAP:9902
TS23: pelvic smooth muscle Present GUDMAP:9902 expression is weak.
TS23: perihilar interstitium Present GUDMAP:9902
TS23: maturing nephron Present GUDMAP:9902
TS23: renal interstitium Present GUDMAP:9902
TS23: late tubule Present GUDMAP:9902
TS23: pretubular aggregate Absent GUDMAP:9902
TS23: ureteric tip Absent GUDMAP:9902
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:9902
TS23: renal vesicle Absent GUDMAP:9902
TS23: comma-shaped body Absent GUDMAP:9902
TS23: s-shaped body Absent GUDMAP:9902
TS23: capillary loop renal corpuscle Absent GUDMAP:9902
TS23: maturing renal corpuscle Absent GUDMAP:9902
TS23: cortical collecting duct Absent GUDMAP:9902
TS23: renal cortical vasculature Absent GUDMAP:9902
TS23: immature loop of Henle Absent GUDMAP:9902
TS23: renal medullary vasculature Absent GUDMAP:9902
TS23: medullary collecting duct Absent GUDMAP:9902
TS23: pelvic urothelial lining Absent GUDMAP:9902
TS23: developing capillary loop stage nephron group Absent GUDMAP:9902
TS23: collecting duct Absent GUDMAP:9902
TS23: renal vasculature Absent GUDMAP:9902
TS23: early nephron Absent GUDMAP:9902
TS23: cap mesenchyme Ambiguous GUDMAP:9902
TS23: cortical renal tubule of maturing nephron group Present GUDMAP:9902

Specimen GUDMAP:9903: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: ureter Present GUDMAP:9903
TS23: ureteral mesenchyme Present GUDMAP:9903
TS23: ureteral smooth muscle layer Present GUDMAP:9903 very weak expression.
TS23: ureteral mesenchyme outer layer Present GUDMAP:9903
TS23: urothelium of ureter Absent GUDMAP:9903


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory