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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5540703
Gene symbol: Tmem100
Gene name: transmembrane protein 100
Probe: RIKEN clone 1810057C19 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:7423: embryonic day 10.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS17: genitourinary system Present GUDMAP:7423
TS17: mesonephros Present GUDMAP:7423
TS17: mesonephric tubule Present GUDMAP:7423 signal appears to be restricted to the mesonephric glomeruli
TS17: cranial mesonephric tubule Present GUDMAP:7423
TS17: nephric duct, metanephric portion Present GUDMAP:7423
TS17: genitourinary system mesenchyme Present GUDMAP:7423
TS17: metanephric mesenchyme Present Regionally restricted GUDMAP:7423 dorsal expression; signal restricted to the dorsal mesenchyme
TS17: gonad primordium Absent GUDMAP:7423
TS17: nephric duct, mesonephric portion Absent GUDMAP:7423
TS17: caudal mesonephric tubule Present GUDMAP:7423
Specimen GUDMAP:7424: embryonic day 12.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS20: male reproductive system Present GUDMAP:7424
TS20: testis Present GUDMAP:7424
TS20: primary sex cord Present GUDMAP:7424
TS20: mesonephros of male Present GUDMAP:7424
TS20: mesonephric mesenchyme of male Present Regionally restricted GUDMAP:7424 caudal expression; restricted signal in two regions of the caudal mesonephros one around the nephric duct and another close to the testis
TS20: urogenital mesentery Absent GUDMAP:7424
TS20: paramesonephric duct of male, mesonephric portion Absent GUDMAP:7424
Specimen GUDMAP:7425: embryonic day 12.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS20: female reproductive system Absent GUDMAP:7425
TS20: ovary Absent GUDMAP:7425
TS20: mesonephros of female Absent GUDMAP:7425
TS20: urogenital mesentery Absent GUDMAP:7425
Specimen GUDMAP:7426: embryonic day 12.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS20: urinary system Present GUDMAP:7426
TS20: metanephros Present GUDMAP:7426
TS20: early nephron Present GUDMAP:7426
TS20: ureter Absent GUDMAP:7426
TS20: urogenital mesentery Absent GUDMAP:7426
Specimen GUDMAP:7752: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: bladder Present GUDMAP:7752
TS23: vasculature of bladder Present GUDMAP:7752
Specimen GUDMAP:7753: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: male reproductive system Present GUDMAP:7753
TS23: testis Present GUDMAP:7753
TS23: developing vasculature of testis Present GUDMAP:7753
TS23: coelomic vessel Present GUDMAP:7753
TS23: interstitial vessel Present GUDMAP:7753
TS23: mesonephros of male Present GUDMAP:7753
TS23: mesonephric mesenchyme of male Present Regionally restricted GUDMAP:7753 restricted signal in mesenchyme; likely to reflect the pattern in seen in the WISH where two specific subregions of the caudal mesonephros were seen
TS23: seminiferous cord Present GUDMAP:7753 weak signal
Specimen GUDMAP:7754: postnatal adult (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: metanephros Absent GUDMAP:7754
Specimen GUDMAP:7820: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: female reproductive system Present GUDMAP:7820
TS23: ovary Present GUDMAP:7820
TS23: mesonephros of female Present GUDMAP:7820 strong signal in blood vessels of mesonephros
TS23: mesonephric mesenchyme of female Present Regionally restricted GUDMAP:7820 signal restricted to mesenchyme surrounding paramesonephric duct
TS23: paramesonephric duct of female, mesonephric portion Present GUDMAP:7820 uncertain signal in epithelium of duct; weak signal in mesenchyme of duct
TS23: degenerating mesonephric portion of nephric duct of female Ambiguous GUDMAP:7820
Specimen GUDMAP:8886: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: urinary system Present GUDMAP:8886
TS23: metanephros Present Regionally restricted GUDMAP:8886
TS23: nephrogenic zone Present GUDMAP:8886
TS23: pretubular aggregate Present GUDMAP:8886
TS23: renal cortex Present Regionally restricted GUDMAP:8886
TS23: renal vesicle Present Regionally restricted GUDMAP:8886 proximal expression; renal vesicles show polarized expression in the proximal end
TS23: comma-shaped body Present Regionally restricted GUDMAP:8886 proximal expression
TS23: lower limb of comma-shaped body Present GUDMAP:8886
TS23: s-shaped body Present Regionally restricted GUDMAP:8886 proximal expression
TS23: proximal segment of s-shaped body Present GUDMAP:8886
TS23: parietal epithelium of s-shaped body Present GUDMAP:8886
TS23: renal cortical vasculature Present Regionally restricted GUDMAP:8886
TS23: renal cortical arterial system Present GUDMAP:8886 signal detected in endothelial layer of arteries
TS23: early nephron Present GUDMAP:8886
TS23: nephrogenic interstitium Absent GUDMAP:8886
TS23: cap mesenchyme Absent GUDMAP:8886
TS23: ureteric tip Absent GUDMAP:8886
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:8886
TS23: upper limb of comma-shaped body Absent GUDMAP:8886
TS23: renal connecting tubule of s-shaped body Absent GUDMAP:8886
TS23: distal segment of s-shaped body Absent GUDMAP:8886
TS23: medial segment of s-shaped body Absent GUDMAP:8886
TS23: visceral epithelium of s-shaped body Absent GUDMAP:8886
TS23: capillary loop renal corpuscle Absent GUDMAP:8886
TS23: maturing renal corpuscle Absent GUDMAP:8886
TS23: cortical renal tubule Absent GUDMAP:8886
TS23: cortical early proximal tubule Absent GUDMAP:8886
TS23: anlage of loop of Henle of cortical renal tubule Absent GUDMAP:8886
TS23: cortical early distal tubule Absent GUDMAP:8886
TS23: renal connecting tubule Absent GUDMAP:8886
TS23: cortical collecting duct Absent GUDMAP:8886
TS23: renal cortical interstitium Absent GUDMAP:8886
TS23: renal cortical venous system Absent GUDMAP:8886
TS23: developing capillary loop stage nephron group Absent GUDMAP:8886
TS23: maturing nephron Absent GUDMAP:8886
TS23: collecting duct Absent GUDMAP:8886
TS23: renal interstitium Absent GUDMAP:8886
TS23: late tubule Absent GUDMAP:8886
TS23: immature loop of Henle Absent GUDMAP:8886
TS23: straight limb of immature loop of Henle Absent GUDMAP:8886
TS23: bend of immature loop of Henle Absent GUDMAP:8886
TS23: renal medullary interstitium Absent GUDMAP:8886
TS23: renal medullary venous system Absent GUDMAP:8886
TS23: renal medullary capillary Absent GUDMAP:8886
TS23: medullary collecting duct Absent GUDMAP:8886
TS23: renal calyx Absent GUDMAP:8886
TS23: renal pelvis Absent GUDMAP:8886
TS23: pelvic urothelial lining Absent GUDMAP:8886
TS23: pelvic smooth muscle Absent GUDMAP:8886
TS23: perihilar interstitium Absent GUDMAP:8886
Specimen GUDMAP:8887: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: urothelium of ureter Absent GUDMAP:8887
TS23: superficial cell layer of ureter Absent GUDMAP:8887
TS23: intermediate cell layer of ureter Absent GUDMAP:8887
TS23: basal cell layer of ureter Absent GUDMAP:8887
TS23: ureteral mesenchyme Absent GUDMAP:8887
TS23: ureteral mesenchyme subepithelial layer Absent GUDMAP:8887
TS23: ureteral smooth muscle layer Absent GUDMAP:8887
TS23: ureteral smooth muscle layer smooth muscle component Absent GUDMAP:8887
TS23: ureteral smooth muscle layer interstitium Absent GUDMAP:8887
TS23: ureteral mesenchyme outer layer Absent GUDMAP:8887
Specimen GUDMAP:8888: embryonic day 15.5 (more )
Note: This assay's probe was visualized using BM purple (blue). This section was also subjected to immunohistochemistry with an anti-Wt1 antibody visualized using DAB (orange).
Structure Level Pattern Image Note
TS23: urinary system Present GUDMAP:8888
TS23: metanephros Present Regionally restricted GUDMAP:8888
TS23: nephrogenic zone Present GUDMAP:8888
TS23: pretubular aggregate Present GUDMAP:8888
TS23: renal cortex Present Regionally restricted GUDMAP:8888
TS23: renal vesicle Present Regionally restricted GUDMAP:8888 proximal expression; majority of renal vesicles show polarized expression in the proximal end; subset of early renal vesicles show homogenous expression
TS23: comma-shaped body Present Regionally restricted GUDMAP:8888 proximal expression
TS23: lower limb of comma-shaped body Present GUDMAP:8888
TS23: s-shaped body Present Regionally restricted GUDMAP:8888 proximal expression
TS23: proximal segment of s-shaped body Present GUDMAP:8888
TS23: parietal epithelium of s-shaped body Present GUDMAP:8888
TS23: renal cortical vasculature Present Regionally restricted GUDMAP:8888
TS23: renal cortical arterial system Present GUDMAP:8888 signal detected in endothelial layer of arteries
TS23: early nephron Present GUDMAP:8888
TS23: nephrogenic interstitium Absent GUDMAP:8888
TS23: cap mesenchyme Absent GUDMAP:8888
TS23: ureteric tip Absent GUDMAP:8888
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:8888
TS23: upper limb of comma-shaped body Absent GUDMAP:8888
TS23: renal connecting tubule of s-shaped body Absent GUDMAP:8888
TS23: distal segment of s-shaped body Absent GUDMAP:8888
TS23: medial segment of s-shaped body Absent GUDMAP:8888
TS23: visceral epithelium of s-shaped body Absent GUDMAP:8888
TS23: capillary loop renal corpuscle Absent GUDMAP:8888
TS23: maturing renal corpuscle Absent GUDMAP:8888
TS23: cortical renal tubule Absent GUDMAP:8888
TS23: cortical early proximal tubule Absent GUDMAP:8888
TS23: anlage of loop of Henle of cortical renal tubule Absent GUDMAP:8888
TS23: cortical early distal tubule Absent GUDMAP:8888
TS23: renal connecting tubule Absent GUDMAP:8888
TS23: cortical collecting duct Absent GUDMAP:8888
TS23: renal cortical interstitium Absent GUDMAP:8888
TS23: renal cortical venous system Absent GUDMAP:8888
TS23: developing capillary loop stage nephron group Absent GUDMAP:8888
TS23: maturing nephron Absent GUDMAP:8888
TS23: collecting duct Absent GUDMAP:8888
TS23: renal interstitium Absent GUDMAP:8888
TS23: late tubule Absent GUDMAP:8888
TS23: immature loop of Henle Absent GUDMAP:8888
TS23: straight limb of immature loop of Henle Absent GUDMAP:8888
TS23: bend of immature loop of Henle Absent GUDMAP:8888
TS23: renal medullary interstitium Absent GUDMAP:8888
TS23: renal medullary venous system Absent GUDMAP:8888
TS23: renal medullary capillary Absent GUDMAP:8888
TS23: medullary collecting duct Absent GUDMAP:8888
TS23: renal calyx Absent GUDMAP:8888
TS23: renal pelvis Absent GUDMAP:8888
TS23: pelvic urothelial lining Absent GUDMAP:8888
TS23: pelvic smooth muscle Absent GUDMAP:8888
TS23: perihilar interstitium Absent GUDMAP:8888
Specimen GUDMAP:9069: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: male reproductive system Present Regionally restricted GUDMAP:9069
TS21: nephric duct of male, rest of Present Regionally restricted GUDMAP:9069
TS21: mesenchyme of nephric duct of male Present GUDMAP:9069
TS21: testis Present Regionally restricted GUDMAP:9069
TS21: primary sex cord Present GUDMAP:9069 weak signal detected
TS21: mesonephric tubule of male Absent GUDMAP:9069
TS21: nephric duct of male, mesonephric portion Absent GUDMAP:9069
TS21: paramesonephric duct of male, mesonephric portion Absent GUDMAP:9069
TS21: coelomic epithelium of male mesonephros Absent GUDMAP:9069
TS21: epithelium of nephric duct of male Absent GUDMAP:9069
TS21: epithelium of rest of paramesonephric duct of male Absent GUDMAP:9069
TS21: coelomic epithelium of testis Absent GUDMAP:9069
TS21: interstitium of the testis Absent GUDMAP:9069
TS21: mesonephros of male Ambiguous GUDMAP:9069 signal seen in the caudal mesenchyme may have some mesonephros component
TS21: mesonephric mesenchyme of male Ambiguous GUDMAP:9069 signal seen in the caudal mesenchyme may have some mesonephros component
TS21: paramesonephric duct of male, rest of Ambiguous GUDMAP:9069
TS21: mesenchyme of rest of paramesonephric duct of male Ambiguous GUDMAP:9069
Specimen GUDMAP:9070: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: urinary system Present Regionally restricted GUDMAP:9070
TS21: metanephros Present Regionally restricted GUDMAP:9070 expression in structure on lateral edges on surface of metanephros which may be subset of renal capsule or mesentery
TS21: nephrogenic zone Present GUDMAP:9070
TS21: early nephron Present GUDMAP:9070
TS21: urogenital mesentery Ambiguous GUDMAP:9070
TS21: renal capsule Ambiguous GUDMAP:9070
TS21: developing vasculature of metanephros Ambiguous GUDMAP:9070 possible expression in the vasculature of the metanephros and associated with the smaller vessels of the aorta
Specimen GUDMAP:9071: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: urogenital sinus Present Regionally restricted GUDMAP:9071 weak signal detected in the sinus rostral to the bladder where the nephric ducts meet
TS21: primitive bladder Absent GUDMAP:9071
Specimen GUDMAP:9072: embryonic day 12.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: mesonephros of female Absent GUDMAP:9072
TS20: ovary Absent GUDMAP:9072
Specimen GUDMAP:9073: embryonic day 12.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: urinary system Present GUDMAP:9073
TS20: metanephros Present GUDMAP:9073
TS20: early nephron Ambiguous GUDMAP:9073
TS20: developing vasculature of metanephros Ambiguous GUDMAP:9073 possible expression in the vasculature of the early tubule and the smaller vessels associated with the aorta
TS20: nephrogenic zone Present GUDMAP:9073
Specimen GUDMAP:14173: postnatal day 0 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS27: metanephros Present GUDMAP:14173
TS27: nephrogenic zone Present GUDMAP:14173
TS27: cap mesenchyme Present GUDMAP:14173
TS27: pretubular aggregate Present GUDMAP:14173
TS27: renal cortex Present GUDMAP:14173
TS27: renal vesicle Present GUDMAP:14173
TS27: s-shaped body Present GUDMAP:14173
TS27: renal medulla Present GUDMAP:14173
TS27: inner renal medulla Present GUDMAP:14173
TS27: inner medullary interstitium Present GUDMAP:14173
TS27: nephrogenic interstitium Absent GUDMAP:14173
TS27: ureteric tip Absent GUDMAP:14173
TS27: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14173
TS27: capillary loop renal corpuscle Absent GUDMAP:14173
TS27: maturing renal corpuscle Absent GUDMAP:14173
TS27: mature renal corpuscle Absent GUDMAP:14173
TS27: cortical renal tubule Absent GUDMAP:14173
TS27: cortical collecting duct Absent GUDMAP:14173
TS27: renal cortical interstitium Absent GUDMAP:14173
TS27: renal cortical vasculature Absent GUDMAP:14173
TS27: proximal renal vesicle Present GUDMAP:14173
TS27: renal connecting segment of renal vesicle Absent GUDMAP:14173
TS27: distal renal vesicle Absent GUDMAP:14173
TS27: proximal segment of s-shaped body Present GUDMAP:14173
TS27: renal connecting tubule of s-shaped body Absent GUDMAP:14173
TS27: distal segment of s-shaped body Absent GUDMAP:14173
TS27: medial segment of s-shaped body Absent GUDMAP:14173
TS27: renal medullary interstitium Present GUDMAP:14173
TS27: outer renal medulla Absent GUDMAP:14173
TS27: loop of Henle, outer medullary portion Absent GUDMAP:14173
TS27: outer medullary interstitium Absent GUDMAP:14173
TS27: outer medullary collecting duct Absent GUDMAP:14173
TS27: loop of Henle, inner medullary portion Absent GUDMAP:14173
TS27: inner medullary collecting duct Absent GUDMAP:14173
TS27: renal medullary vasculature Absent GUDMAP:14173
TS27: renal pelvis Absent GUDMAP:14173
Specimen GUDMAP:14174: postnatal day 2 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS27: metanephros Present GUDMAP:14174
TS27: nephrogenic zone Present GUDMAP:14174
TS27: cap mesenchyme Present GUDMAP:14174
TS27: pretubular aggregate Present GUDMAP:14174
TS27: renal cortex Present GUDMAP:14174
TS27: renal vesicle Present GUDMAP:14174
TS27: s-shaped body Ambiguous GUDMAP:14174
TS27: renal medulla Present GUDMAP:14174
TS27: nephrogenic interstitium Absent GUDMAP:14174
TS27: ureteric tip Absent GUDMAP:14174
TS27: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14174
TS27: capillary loop renal corpuscle Absent GUDMAP:14174
TS27: maturing renal corpuscle Absent GUDMAP:14174
TS27: mature renal corpuscle Absent GUDMAP:14174
TS27: cortical renal tubule Absent GUDMAP:14174
TS27: cortical collecting duct Absent GUDMAP:14174
TS27: renal cortical interstitium Absent GUDMAP:14174
TS27: renal cortical vasculature Absent GUDMAP:14174
TS27: proximal renal vesicle Present GUDMAP:14174
TS27: renal connecting segment of renal vesicle Absent GUDMAP:14174
TS27: distal renal vesicle Absent GUDMAP:14174
TS27: proximal segment of s-shaped body Ambiguous GUDMAP:14174
TS27: renal connecting tubule of s-shaped body Absent GUDMAP:14174
TS27: distal segment of s-shaped body Absent GUDMAP:14174
TS27: medial segment of s-shaped body Absent GUDMAP:14174
TS27: renal medullary interstitium Ambiguous GUDMAP:14174
TS27: renal pelvis Absent GUDMAP:14174
Specimen GUDMAP:14175: postnatal day 4 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS27: metanephros Present GUDMAP:14175
TS27: nephrogenic zone Present GUDMAP:14175
TS27: renal cortex Present GUDMAP:14175
TS27: renal vesicle Present GUDMAP:14175
TS27: s-shaped body Present GUDMAP:14175 Younger S-shaped bodies show strong proximal segment expression, with the expression signal weakening with older, more mature S-shaped bodies.
TS27: renal medulla Present GUDMAP:14175
TS27: inner renal medulla Present GUDMAP:14175
TS27: inner medullary interstitium Present GUDMAP:14175
TS27: nephrogenic interstitium Absent GUDMAP:14175
TS27: ureteric tip Absent GUDMAP:14175
TS27: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14175
TS27: capillary loop renal corpuscle Absent GUDMAP:14175
TS27: maturing renal corpuscle Absent GUDMAP:14175
TS27: mature renal corpuscle Absent GUDMAP:14175
TS27: cortical renal tubule Absent GUDMAP:14175
TS27: cortical collecting duct Absent GUDMAP:14175
TS27: renal cortical interstitium Absent GUDMAP:14175
TS27: renal cortical vasculature Absent GUDMAP:14175
TS27: proximal renal vesicle Present GUDMAP:14175
TS27: renal connecting segment of renal vesicle Absent GUDMAP:14175
TS27: distal renal vesicle Absent GUDMAP:14175
TS27: proximal segment of s-shaped body Present GUDMAP:14175
TS27: renal connecting tubule of s-shaped body Absent GUDMAP:14175
TS27: distal segment of s-shaped body Absent GUDMAP:14175
TS27: medial segment of s-shaped body Absent GUDMAP:14175
TS27: renal medullary interstitium Present GUDMAP:14175
TS27: outer renal medulla Absent GUDMAP:14175
TS27: loop of Henle, outer medullary portion Absent GUDMAP:14175
TS27: outer medullary interstitium Absent GUDMAP:14175
TS27: outer medullary collecting duct Absent GUDMAP:14175
TS27: loop of Henle, inner medullary portion Absent GUDMAP:14175
TS27: inner medullary collecting duct Absent GUDMAP:14175
TS27: renal medullary vasculature Absent GUDMAP:14175
TS27: renal pelvis Absent GUDMAP:14175
Specimen GUDMAP:14176: postnatal day 6 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: metanephros Absent GUDMAP:14176
TS28: nephrogenic interstitium Absent GUDMAP:14176
TS28: ureteric tip Absent GUDMAP:14176
TS28: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14176
TS28: renal cortex Absent GUDMAP:14176
TS28: renal medulla Absent GUDMAP:14176
TS28: renal pelvis Absent GUDMAP:14176
TS28: nephrogenic zone Absent GUDMAP:14176
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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