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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5538970
Gene symbol: Cldn6
Gene name: claudin 6
Probe: NIA clone H3076D06
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:73: embryonic day 10.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS17: limb Present Regionally restricted GUDMAP:73 Expression in the hindlimb bud; Expression in the apical ectodermal ridge; Expression in the anterior and posterior ends of the proximal hindlimb bud
TS17: organ system Present GUDMAP:73
TS17: nephric duct, metanephric portion Present GUDMAP:73
TS17: metanephric mesenchyme Absent GUDMAP:73
TS17: mesonephros Present GUDMAP:73
TS17: genitourinary system Present GUDMAP:73
TS17: mesonephros mesenchyme Absent GUDMAP:73
TS17: mesonephric tubule Absent GUDMAP:73
TS17: nephric duct, mesonephric portion Present GUDMAP:73
TS17: nephric duct Present GUDMAP:73

Specimen GUDMAP:74: embryonic day 12.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: organ system Present GUDMAP:74
TS20: ureter Present GUDMAP:74
TS20: metanephros Present GUDMAP:74
TS20: ureteric tip Present GUDMAP:74
TS20: primitive collecting duct Present GUDMAP:74
TS20: ureteric trunk Present GUDMAP:74
TS20: urinary system Present GUDMAP:74
TS20: renal capsule Absent GUDMAP:74
TS20: nephrogenic interstitium Absent GUDMAP:74
TS20: cap mesenchyme Absent GUDMAP:74
TS20: renal interstitium Absent GUDMAP:74
TS20: developing vasculature of metanephros Absent GUDMAP:74
TS20: reproductive system Present GUDMAP:74 Strong expression detected in the nephric duct, mesonephric portion; paramesonephric duct, mesonephric portion; nephric duct, rest of; paramesonephric duct, rest of; and mesonephric tubules (both rostral and caudal tubules), however the sex is unknown.

Specimen GUDMAP:8811: embryonic day 15.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS23: metanephros Present GUDMAP:8811
TS23: nephrogenic zone Present GUDMAP:8811
TS23: renal cortex Present GUDMAP:8811
TS23: renal vesicle Present GUDMAP:8811
TS23: comma-shaped body Present GUDMAP:8811 The upper limb of the comma-shaped bodies shows stronger expression than the lower limb.
TS23: s-shaped body Present GUDMAP:8811
TS23: cortical renal tubule Present GUDMAP:8811
TS23: cortical early proximal tubule Present GUDMAP:8811
TS23: anlage of loop of Henle of cortical renal tubule Present GUDMAP:8811
TS23: cortical early distal tubule Present GUDMAP:8811
TS23: cortical collecting duct Present GUDMAP:8811
TS23: renal cortical venous system Present GUDMAP:8811
TS23: renal medulla Present GUDMAP:8811
TS23: immature loop of Henle Present GUDMAP:8811
TS23: renal medullary venous system Present GUDMAP:8811
TS23: medullary collecting duct Present GUDMAP:8811
TS23: renal pelvis Present GUDMAP:8811
TS23: pelvic urothelial lining Present GUDMAP:8811
TS23: renal vein Present GUDMAP:8811
TS23: developing capillary loop stage nephron group Present GUDMAP:8811
TS23: maturing nephron Present GUDMAP:8811
TS23: early nephron Present GUDMAP:8811
TS23: late tubule Present GUDMAP:8811
TS23: maturing renal corpuscle Absent GUDMAP:8811 Stage IV renal corpuscles show no expression.

Specimen GUDMAP:8812: postnatal adult (more )
Note: Labeling was visualized using NBT/BCIP. Annotators reported some nuclear staining which may be background.
Structure Level Pattern Image Note
TS28: metanephros Present GUDMAP:8812
TS28: renal cortex Present GUDMAP:8812
TS28: mature renal corpuscle Present GUDMAP:8812 Expression in renal corpuscles appeared to be restricted to the juxtamedullary nephrons.
TS28: glomerular tuft Present GUDMAP:8812
TS28: Bowman's capsule of mature renal corpuscle Present GUDMAP:8812
TS28: parietal epithelium of mature renal corpuscle Present GUDMAP:8812
TS28: cortical renal tubule Present GUDMAP:8812
TS28: renal proximal tubule Present GUDMAP:8812
TS28: distal convoluted tubule Present GUDMAP:8812
TS28: cortical collecting duct Present GUDMAP:8812
TS28: renal cortical arterial system Present GUDMAP:8812
TS28: arcuate artery Present GUDMAP:8812
TS28: renal medulla Present GUDMAP:8812
TS28: outer renal medulla Present GUDMAP:8812
TS28: outer stripe of outer medulla Present GUDMAP:8812
TS28: distal straight tubule of outer stripe of outer medulla Present GUDMAP:8812
TS28: proximal straight tubule, cortical portion Present GUDMAP:8812
TS28: renal proximal convoluted tubule Present GUDMAP:8812 Expression in the proximal convoluted tubule is restricted to a subset of these tubules.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory