Gene Expression Data
Assay Details
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Assay
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Reference:
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J:77750
Kwon YT, et al., An essential role of N-terminal arginylation in cardiovascular development. Science. 2002 Jul 5;297(5578):96-9
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5525125
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Gene symbol:
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Pecam1
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Gene name:
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platelet/endothelial cell adhesion molecule 1
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Antibody:
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MEC 13.3
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
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Results
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Specimen
2C:
embryonic day 9.5
(more )
Specimen
2C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
2D:
embryonic day 9.5; Ate1tm1Avar/Ate1 +
(more )
Specimen
2D:
(close )
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Genetic Background:
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either: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Ate1tm1Avar/Ate1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: blood vessel |
Present |
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2D
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The formation of vessels that normally sprout from intersegmental artery and cross the dorsal midline was suppressed in this mutant.
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Specimen
2E:
embryonic day 13.5
(more )
Specimen
2E:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
2F:
embryonic day 13.5; Ate1tm1Avar/Ate1 +
(more )
Specimen
2F:
(close )
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Genetic Background:
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either: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Ate1tm1Avar/Ate1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: yolk sac |
Present |
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2F
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Blood vessels terminate prematurely in this mutant and angiogenic remodeling is perturbed.
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Specimen
2G:
embryonic day 9.5
(more )
Specimen
2G:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
2H:
embryonic day 9.5; Ate1tm1Avar/Ate1 +
(more )
Specimen
2H:
(close )
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Genetic Background:
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either: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Ate1tm1Avar/Ate1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
S3D:
embryonic day 13.5
(more )
Specimen
S3D:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
S3E:
(close )
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Genetic Background:
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either: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Ate1tm1Avar/Ate1tm1Avar
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: yolk sac |
Present |
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S3E
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Blood vessels are smaller in the mutant embryo.
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Specimen
S3F:
embryonic day 13.5
(more )
Specimen
S3F:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
S3G:
(close )
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Genetic Background:
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either: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Ate1tm1Avar/Ate1tm1Avar
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: blood vessel |
Present |
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S3G
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Expression is in normal intersomitic arteries but there is poor development of vessels in this mutant.
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Specimen
S3H:
embryonic day 13.5
(more )
Specimen
S3H:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
S3I:
(close )
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Genetic Background:
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either: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Ate1tm1Avar/Ate1tm1Avar
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: blood vessel |
Present |
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S3I
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The mutant has impaired angiogenesis.
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Specimen
S3J:
embryonic day 13.5
(more )
Specimen
S3J:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
S3K:
(close )
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Genetic Background:
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either: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Ate1tm1Avar/Ate1tm1Avar
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: blood vessel |
Present |
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S3K
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The mutant has impaired angiogenesis.
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Specimen
S4C:
embryonic day 15.5
(more )
Specimen
S4C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: yolk sac |
Present |
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S4C
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Expression is in blood vessels.
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Specimen
S4C:
(close )
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Genetic Background:
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either: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Ate1tm1Avar/Ate1tm1Avar
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: yolk sac |
Present |
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S4D
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Expression is in blood vessels and the pattern is different in this mutant.
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