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Gene Expression Data
Assay Details
Assay
Reference: J:49126 Zachgo J, et al., Genetic interactions suggest that Danforth's short tail (Sd) is a gain-of-function mutation. Dev Genet. 1998;23(1):86-96
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5510726
Gene symbol: Etl4
Gene name: enhancer trap locus 4
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 8.5; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS13: notochord Present 1A Expressed in presumptive notochord cells along the ventral midline.
TS13: 1st branchial arch Present 1A
Specimen 1B: embryonic day 8.5; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Note: Double labeled: blue - Etl4 reporter; brown - T (assay MGI:5510782).
Structure Level Pattern Image Note
TS13: notochord Present 1B
Specimen 1C: embryonic day 9.5; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch Present 1C
TS15: 2nd branchial arch Present 1C
TS15: 3rd branchial arch Present 1C
TS15: notochord Present 1C
TS15: limb ectoderm Present Regionally restricted 1C Expressed in the whole surface area.
Specimen 1D: embryonic day 9.5; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS15: ear Present 1D
TS15: eye Present 1D
TS15: notochord Present 1D
TS15: urogenital ridge Present 1D
TS15: limb ectoderm Present Regionally restricted 1D Expressed in the whole surface area.
TS15: trunk Present 1D Expressed in the Wolff'schen ridge between the limb buds.
Specimen 1E: embryonic day 10.5; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS17: branchial arch Present 1E
TS17: ear Present 1E
TS17: eye Present 1E
TS17: notochord Present 1E
TS17: urogenital ridge Present 1E
TS17: limb ectoderm Present Regionally restricted 1E Expression is restricted to the apical region.
Specimen 1F: embryonic day 10.5; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component Present 1F
TS17: 1st branchial arch maxillary component Present 1F
TS17: 1st branchial groove Present 1F
TS17: 2nd branchial arch Present 1F
TS17: 3rd branchial arch Present 1F
TS17: 4th branchial arch Present 1F
TS17: otocyst Present Regionally restricted 1F Expressed in the rostral otocyst.
Specimen 1G: embryonic day 11.5; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS19: ear Present 1G
TS19: eye Present 1G
TS19: mesonephros mesenchyme Present 1G
TS19: notochord Present 1G
TS19: urogenital ridge Present 1G
TS19: apical ectodermal ridge Present 1G
TS19: embryo Present Regionally restricted 1G Expressed in dorsal subepidermal cells as stripes.
Specimen 1H: embryonic day 11.5; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS19: gonad Present Regionally restricted 1H Expressed in some cells in the testes cords.
TS19: urinary system Present Regionally restricted 1H Expressed in cells rostral to the mesonephros, probably remnants of the pronephros.
TS19: metanephros Present 1H
Specimen 1I: embryonic day 13.5; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS21: notochord Present 1I
TS21: nucleus pulposus Present 1I Expressed in the prospective nuclei pulposi of the intervertebral discs.
Specimen 2E: embryonic day 13.5; Etl4Gt(6LSN)6029Gos/Etl4Gt(6LSN)6029Gos (more )
Structure Level Pattern Image Note
TS21: notochord Present 2E
Specimen not shown: embryonic day 6.5; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS9: embryo Absent
Specimen not shown: embryonic day 9.5; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component mesenchyme Present
TS15: 1st branchial arch maxillary component Present
TS15: 1st branchial groove Present
TS15: otocyst Present Regionally restricted Expressed in the rostral otocyst.
Specimen not shown: embryonic day 10.0; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS16: embryo Present Regionally restricted Expressed in stripes of subepidermal cells over the dorsal third of the neural tube, and cells between the neural tube and the somites.
Specimen not shown: embryonic day 10.5; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS17: branchial arch ectoderm Present Expressed in the epithelial layer.
TS17: branchial arch mesenchyme Present Expressed in the subepithelial layer.
Specimen not shown: embryonic day 12.5; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS20: mesenchyme of metanephros Present Highest expression during embryonic development.
TS20: ear Present
TS20: eye Present
TS20: urogenital ridge Present
Specimen not shown: embryonic day 14.0; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS22: limb digit Present Single cells Expressed in only few dispersed cells on the tips of the developing digits.
Specimen not shown: embryonic day 14.5; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS22: nucleus pulposus Present Expressed in the notochord.
Specimen not shown: postnatal newborn; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS27: nucleus pulposus Absent
Specimen not shown: postnatal adult; Etl4Gt(6LSN)6029Gos/Etl4+ (more )
Structure Level Pattern Image Note
TS28: nucleus pulposus Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory