About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:182715 Monahan P, et al., p21, an important mediator of quiescence during pituitary tumor formation, is dispensable for normal pituitary development during embryogenesis. Mech Dev. 2012 Jan-Feb;128(11-12):640-52
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5507698
Gene symbol: Cdkn1a
Gene name: cyclin dependent kinase inhibitor 1A
Antibody: anti-p21
Detection system: Secondary antibody coupled to Cy3
Assay notes: Fixative was 3.8% formaldehyde.
Results
Specimen 1A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: Rathke's pouch Present Regionally restricted 1A Expression is at the junction of Rathke's pouch and the oral ectoderm.
TS17: oral epithelium Present Regionally restricted 1A Expression is at the junction of Rathke's pouch and the oral ectoderm.
Specimen 1B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: Rathke's pouch Present Single cells 1B Expression is in scattered cells at the ventral aspect.
TS19: oral epithelium Present Regionally restricted 1B Expression is in cells directly below Rathke's pouch.
Specimen 1C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: remnant of Rathke's pouch Present Single cells 1C
Specimen 1D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pituitary gland Present Single cells 1D Expression is in sparsely scattered cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory