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Gene Expression Data
Assay Details
Assay
Reference: J:77812 Perriton CL, et al., Sonic hedgehog signaling from the urethral epithelium controls external genital development. Dev Biol. 2002 Jul 1;247(1):26-46
Assay type: RNA in situ
MGI Accession ID: MGI:5505589
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Probe: Bmp4 probe44
Visualized with: Alkaline phosphatase
Results
Specimen 3C E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: genitourinary system Present Regionally restricted 3C E10.5 Expression in genital field on either side of cloaca.
Specimen 3C E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: genital swelling of genital tubercle Present Regionally restricted 3C E11.5 Expression in anterior/dorsal swelling.
Specimen 3C E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: genital tubercle Present Regionally restricted 3C E12.5 Expression restricted to dorsal and ventral surfaces of genital tubercle.
Specimen 3C E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: genital tubercle Strong Regionally restricted 3C E13.5 Strong expression on dorsal surface. Rapid growth of dorsal side of tubercle associated with gradual movement of domain toward distal tip.
Specimen 3C E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: preputial gland Present 3C E14.5
TS22: genital tubercle Present Regionally restricted 3C E14.5 Expression in glans.
Specimen 4L: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: genital tubercle Present Regionally restricted 4L Expression in mesenchyme in urethral plate. Expression in glans.
Specimen 4M: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: genital tubercle Present Regionally restricted 4M Expression in dorsal mesenchyme subjacent to dorsal ectoderm.
Specimen 6E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: genitourinary system Present Regionally restricted 6E Expression in mesenchyme surrounding urethral plate.
Specimen 6F: embryonic day 11.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS19: genitourinary system Weak Regionally restricted 6F Weaker expression in similar pattern to wild-type embryo. Expression in two strips lateral to cloacal epithelium.
Specimen 6G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: genitourinary system Present Regionally restricted 6G Expression immediately lateral to urethral plate and throughout entire distal region.
TS21: genital tubercle Present Regionally restricted 6G Expression throughout the glans.
Specimen 6H: embryonic day 13.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS21: genitourinary system Absent 6H No expression in genital region.
TS21: hindgut Present Regionally restricted 6H Expression within and posterior to the cloaca.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory