Gene Expression Data
Assay Details
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Assay
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Reference:
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J:85738
MacLean HE, et al., Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development. Dev Biol. 2003 Oct 1;262(1):51-63
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5505468
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Gene symbol:
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Runx2
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Gene name:
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runt related transcription factor 2
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Probe:
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Cbfa1 cDNA7
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Probe preparation:
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Antisense labelled with S35 RNA
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Results
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Specimen
6A +/+:
embryonic day 15.5
(more  )
Specimen
6A +/+:
(close  )
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Genetic Background:
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involves: BALB/c
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: tibia |
Present |
Regionally restricted |
6A +/+
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Expression was detected in early and late hypertrophic chondrocytes, the perichondrium, and the bone collar.
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Specimen
6A -/-:
(close )
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Genetic Background:
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involves: BALB/c
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Mutant Allele(s):
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Maftm1Glm/Maftm1Glm
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: tibia |
Present |
Regionally restricted |
6A -/-
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Normal expression was detected in early and late hypertrophic chondrocytes, the perichondrium, and the bone collar in the mutant.
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Specimen
not shown E14.5:
embryonic day 14.5
(more )
Specimen
not shown E14.5:
(close )
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Genetic Background:
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involves: BALB/c
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Specimen
not shown E14.5:
(close )
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Genetic Background:
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involves: BALB/c
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Mutant Allele(s):
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Maftm1Glm/Maftm1Glm
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: tibia cartilage condensation |
Present |
Regionally restricted |
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Normal expression was detected in early and late hypertrophic chondrocytes in the mutant.
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Specimen
not shown E18.5:
embryonic day 18.5
(more )
Specimen
not shown E18.5:
(close )
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Genetic Background:
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involves: BALB/c
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: tibia |
Present |
Regionally restricted |
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Expression was detected in early and late hypertrophic chondrocytes.
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Specimen
not shown E18.5:
(close )
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Genetic Background:
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involves: BALB/c
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Mutant Allele(s):
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Maftm1Glm/Maftm1Glm
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: tibia |
Present |
Regionally restricted |
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Normal expression was detected in early and late hypertrophic chondrocytes in the mutant.
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Analysis Tools