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Gene Expression Data
Assay Details
Assay
Reference: J:86839 Liguori GL, et al., Anterior neural plate regionalization in cripto null mutant mouse embryos in the absence of node and primitive streak. Dev Biol. 2003 Dec 15;264(2):537-49
Assay type: RNA in situ
MGI Accession ID: MGI:5504376
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Probe: Otx2 cDNA12
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future midbrain Present 3A
TS13: future prosencephalon Present 3A
Specimen 3A': embryonic day 8.5; Criptotm1Eda/Criptotm1Eda (more )
Structure Level Pattern Image Note
TS13: future midbrain Present 3A' Expression was detected as in wild type.
TS13: future prosencephalon Present 3A' Expression was detected as in wild type.
Specimen Table 1: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future prosencephalon Present Regionally restricted Expression was detected in anterior prosencephalon and diencephalon.
TS13: future midbrain Present
Specimen Table 1: embryonic day 8.5; Criptotm1Eda/Criptotm1Eda (more )
Structure Level Pattern Image Note
TS13: future prosencephalon Present Regionally restricted Expression was detected in anterior prosencephalon and diencephalon.
TS13: future midbrain Present
Specimen 7A: embryonic day 8.5 (more )
Note: Double labeled: blue - Otx2; red - Gbx2 (assay MGI:5504433).
Structure Level Pattern Image Note
TS13: future brain Present Regionally restricted 7A Expression was detected rostral of the isthmus. Staining was juxtaposed to Gbx2 expression.
Specimen 7A': embryonic day 8.5; Criptotm1Eda/Criptotm1Eda (more )
Note: Double labeled: blue - Otx2; red - Gbx2 (assay MGI:5504433).
Structure Level Pattern Image Note
TS13: future brain Present Regionally restricted 7A' Staining adjacent to Gbx2 expression was maintained in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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