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Gene Expression Data
Assay Details
Assay
Reference: J:59068 Pispa J, et al., Cusp patterning defect in Tabby mouse teeth and its partial rescue by FGF. Dev Biol. 1999 Dec 15;216(2):521-34
Assay type: RNA in situ
MGI Accession ID: MGI:5499546
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Probe: Bmp4 cDNA17
Probe preparation: labelled with S35
Visualized with: Autoradiography
Results
Specimen 5a: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: lower jaw molar Present Regionally restricted 5a Expression in primary enamel knot.
TS22: primary enamel knot Present Regionally restricted 5a Expression in primary enamel knot.
TS22: lower jaw molar mesenchyme Strong 5a
Specimen 5b: embryonic day 14.0; EdaTa/? (more )
Note: the mutation is X-linked; the embryo could have been homozygous or hemizygous
Structure Level Pattern Image Note
TS22: lower jaw molar Weak Regionally restricted 5b Reduced area of expression compared to wild type.
TS22: lower jaw molar mesenchyme Weak Regionally restricted 5b Reduced area of expression compared to wild type.
TS22: primary enamel knot Weak Regionally restricted 5b Reduced area of expression compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory