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Gene Expression Data
Assay Details
Assay
Reference: J:76263 Stricker S, et al., Role of Runx genes in chondrocyte differentiation. Dev Biol. 2002 May 1;245(1):95-108
Assay type: RNA in situ
MGI Accession ID: MGI:5498659
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Probe: Runx2 probe4
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen 2A 13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: metacarpus pre-cartilage condensation Strong Regionally restricted 2A upper left Strong expression in the perichondrium and to a lesser degree within chondrocytes of the metacarpal anlagen.
TS21: forelimb phalanx pre-cartilage condensation Strong Regionally restricted 2A upper left Strong expression in the perichondrium and to a lesser degree within chondrocytes of the proximal phalanges, and in a region corresponding to the future distal phalanges/claws.
TS21: carpus pre-cartilage condensation Absent 2A upper left
TS21: hand joint Absent 2A upper left

Specimen 2B 14.5 upper: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Strong Regionally restricted 2B 14.5 runx2 upper Expressed in the perichondrium, in osteoblasts, and in hypertrophic chondrocytes.

Specimen 2B 15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: humerus Strong Regionally restricted 2B 15.5 runx2 Expressed in the perichondrium, in osteoblasts, and in hypertrophic chondrocytes.

Specimen 2B 14.5 bottom: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: elbow joint primordium Absent 2B 14.5 runx2 bottom No expression in cartilage or perichondrium around the future elbow joint.

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: limb digit Present Regionally restricted Expressed in the perichondrium and the chondrocytes located in the proximal part of the metacarpals and phalanges.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory