About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:77813 Rossi F, et al., p107 and p130 Coordinately regulate proliferation, Cbfa1 expression, and hypertrophic differentiation during endochondral bone development. Dev Biol. 2002 Jul 15;247(2):271-85
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5494956
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Results
Specimen 5G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: humerus pre-cartilage condensation Present 5G

Specimen 5H: embryonic day 12.5; Rbl1tm1Tyj/Rbl1+, Rbl2tm1Tyj/Rbl2+ (more )
Structure Level Pattern Image Note
TS20: humerus pre-cartilage condensation Present 5H

Specimen 5I: embryonic day 12.5; Rbl1tm1Tyj/Rbl1+, Rbl2tm1Tyj/Rbl2tm1Tyj (more )
Structure Level Pattern Image Note
TS20: humerus pre-cartilage condensation Present 5I

Specimen 5J: embryonic day 12.5; Rbl1tm1Tyj/Rbl1tm1Tyj (more )
Structure Level Pattern Image Note
TS20: humerus pre-cartilage condensation Absent 5J

Specimen 5K: embryonic day 12.5; Rbl1tm1Tyj/Rbl1tm1Tyj, Rbl2tm1Tyj/Rbl2+ (more )
Structure Level Pattern Image Note
TS20: humerus pre-cartilage condensation Absent 5K

Specimen 5L: embryonic day 12.5; Rbl1tm1Tyj/Rbl1tm1Tyj, Rbl2tm1Tyj/Rbl2tm1Tyj (more )
Structure Level Pattern Image Note
TS20: humerus pre-cartilage condensation Absent 5L

Specimen 8F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: humerus cartilage condensation Present 8F

Specimen 8G: embryonic day 13.5; Rbl1tm1Tyj/Rbl1+, Rbl2tm1Tyj/Rbl2+ (more )
Structure Level Pattern Image Note
TS21: humerus cartilage condensation Present 8G

Specimen 8H: embryonic day 13.5; Rbl1tm1Tyj/Rbl1+, Rbl2tm1Tyj/Rbl2tm1Tyj (more )
Structure Level Pattern Image Note
TS21: humerus cartilage condensation Present 8H

Specimen 8I: embryonic day 13.5; Rbl1tm1Tyj/Rbl1tm1Tyj (more )
Structure Level Pattern Image Note
TS21: humerus cartilage condensation Weak 8I

Specimen 8J: embryonic day 13.5; Rbl1tm1Tyj/Rbl1tm1Tyj, Rbl2tm1Tyj/Rbl2tm1Tyj (more )
Structure Level Pattern Image Note
TS21: humerus cartilage condensation Absent 8J

Specimen 9K: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: humerus Present Regionally restricted 9K Expression in prehypertrophic and hypertrophic zones.

Specimen 9L: embryonic day 15.5; Rbl1tm1Tyj/Rbl1+, Rbl2tm1Tyj/Rbl2+ (more )
Structure Level Pattern Image Note
TS23: humerus Present Regionally restricted 9L Expression in prehypertrophic and hypertrophic zones.

Specimen 9M: embryonic day 15.5; Rbl1tm1Tyj/Rbl1+, Rbl2tm1Tyj/Rbl2tm1Tyj (more )
Structure Level Pattern Image Note
TS23: humerus Present Regionally restricted 9M Expression in prehypertrophic and hypertrophic zones.

Specimen 9N: embryonic day 15.5; Rbl1tm1Tyj/Rbl1tm1Tyj (more )
Structure Level Pattern Image Note
TS23: humerus Present 9N

Specimen 9O: embryonic day 15.5; Rbl1tm1Tyj/Rbl1tm1Tyj, Rbl2tm1Tyj/Rbl2tm1Tyj (more )
Structure Level Pattern Image Note
TS23: humerus Present Regionally restricted 9O Expression in a subset of cells at the peripery of a central BrdU-negative region

Specimen 10B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: radius cartilage condensation Present Regionally restricted 10B Expression in the BrdU-negative zone.

Specimen 10D: embryonic day 15.5; Rbl1tm1Tyj/Rbl1+, Rbl2tm1Tyj/Rbl2+ (more )
Structure Level Pattern Image Note
TS23: forelimb phalanx Present 10D

Specimen 10F: embryonic day 15.5; Rbl1tm1Tyj/Rbl1tm1Tyj, Rbl2tm1Tyj/Rbl2tm1Tyj (more )
Structure Level Pattern Image Note
TS23: forelimb phalanx Absent 10F


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory