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Gene Expression Data
Assay Details
Assay
Reference: J:72600 Yamagishi H, et al., The Combinatorial Activities of Nkx2.5 and dHAND Are Essential for Cardiac Ventricle Formation. Dev Biol. 2001 Nov 15;239(2):190-203
Assay type: RNA in situ
MGI Accession ID: MGI:5493468
Gene symbol: Myl2
Gene name: myosin, light polypeptide 2, regulatory, cardiac, slow
Probe: MLC2v probe5
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 5E: embryonic day 9.25 (more )
Structure Level Pattern Image Note
TS15: primitive ventricle Present 5E
Specimen 5F: embryonic day 9.25; Nkx2-5tm1Wehi/Nkx2-5tm1Wehi (more )
Structure Level Pattern Image Note
TS15: primitive ventricle Weak 5F
TS15: heart Present Regionally restricted 5F A sharp border between the ventral and dorsal regions.
Specimen 5G: embryonic day 9.25; Hand2tm1Dsr/Hand2tm1Dsr (more )
Structure Level Pattern Image Note
TS15: primitive ventricle Present 5G Expression in this mutant is the same as in wild-type.
TS15: heart atrium Absent 5G
Specimen 5H: embryonic day 9.25; Hand2tm1Dsr/Hand2tm1Dsr, Nkx2-5tm1Wehi/Nkx2-5tm1Wehi (more )
Structure Level Pattern Image Note
TS15: heart Present Single cells 5H Expression is in a small number of cells along the ventral surface, absent everywhere else.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory