Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:171806
Young B, et al., Indian and sonic hedgehogs regulate synchondrosis growth plate and cranial base development and function. Dev Biol. 2006 Nov 1;299(1):272-82
|
Assay type:
|
RNA in situ
|
MGI Accession ID:
|
MGI:5493439
|
Gene symbol:
|
Shh
|
Gene name:
|
sonic hedgehog
|
Probe:
|
Shh cDNA25
|
Probe preparation:
|
Antisense labelled with S35 RNA
|
Visualized with:
|
Autoradiography
|
|
Results
|
Specimen
8B,D:
embryonic day 13.5
(more )
Specimen
8B,D:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: notochord |
Strong |
Regionally restricted |
8D
,
8B
|
Expression was strong in notochord remnants adjacent to incipient spheno-occipital synchondrosis. No expression was seen near the more anterior intrasphenoidal synchondrosis.
|
TS21: oral region |
Present |
Regionally restricted |
8B
,
8D
|
Expression was detected in oral ectoderm.
|
Specimen
8G,I:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
Mutant Allele(s):
|
Ihhtm1Amc/Ihhtm1Amc
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: notochord |
Strong |
Regionally restricted |
8I
,
8G
|
Expression persisted in notochord remnants in the mutant.
|
|