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Gene Expression Data
Assay Details
Assay
Reference: J:104896 Cho JH, et al., Preferential posterior cerebellum defect in BETA2/NeuroD1 knockout mice is the result of differential expression of BETA2/NeuroD1 along anterior-posterior axis. Dev Biol. 2006 Feb 1;290(1):125-38
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5491690
Gene symbol: Neurod1
Gene name: neurogenic differentiation 1
Reporter: lacZ
Direct Detection
Results
Specimen 1E: postnatal month 4; Neurod1tm1Mjts/Neurod1+ (more )
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present 1E

Specimen 1F: postnatal month 4; Neurod1tm1Mjts/Neurod1tm1Mjts (more )
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present 1F Expressing granule cells in knockout mice have a major reduction in numbers in the anterior compartment and are almost completely depleted in the posterior part.

Specimen 3A: embryonic day 17.5; Neurod1tm1Mjts/Neurod1+ (more )
Structure Level Pattern Image Note
TS25: cerebellum Strong Regionally restricted 3A Expression is in the external granule layer.

Specimen 3B: embryonic day 17.5; Neurod1tm1Mjts/Neurod1tm1Mjts (more )
Structure Level Pattern Image Note
TS25: cerebellum Strong Regionally restricted 3B Expression is the same as in wild-type.

Specimen 3C: embryonic day 18.5; Neurod1tm1Mjts/Neurod1+ (more )
Structure Level Pattern Image Note
TS26: cerebellum Strong Regionally restricted 3C Expression is in the external granule layer.

Specimen 3D: embryonic day 18.5; Neurod1tm1Mjts/Neurod1tm1Mjts (more )
Structure Level Pattern Image Note
TS26: cerebellum Strong Regionally restricted 3D Expression is in the external granule layer which has changes in lobulation.

Specimen 3E: postnatal day 1; Neurod1tm1Mjts/Neurod1+ (more )
Structure Level Pattern Image Note
TS27: cerebellum external granule cell layer Strong 3E

Specimen 3F: postnatal day 1; Neurod1tm1Mjts/Neurod1tm1Mjts (more )
Structure Level Pattern Image Note
TS27: cerebellum external granule cell layer Strong 3F This mutant has changes in lobulation.

Specimen 3G: postnatal day 2; Neurod1tm1Mjts/Neurod1+ (more )
Structure Level Pattern Image Note
TS27: cerebellum external granule cell layer Strong 3G

Specimen 3H: postnatal day 2; Neurod1tm1Mjts/Neurod1tm1Mjts (more )
Structure Level Pattern Image Note
TS27: cerebellum external granule cell layer Strong 3H This mutant has changes in lobulation.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory