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Gene Expression Data
Assay Details
Assay
Reference: J:77801 Soo K, et al., Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo. Dev Biol. 2002 Jul 15;247(2):251-70
Assay type: RNA in situ
MGI Accession ID: MGI:5491626
Gene symbol: Fgfr1
Gene name: fibroblast growth factor receptor 1
Probe: Fgfr1 probe6
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5D +/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial arch Present 5D +/+
TS17: head mesenchyme Present Regionally restricted 5D +/+ Expression was detected in the facial mesenchyme.
Specimen 5D -/-: embryonic day 10.5; Twist1tm1Bhr/Twist1tm1Bhr (more )
Structure Level Pattern Image Note
TS17: branchial arch Absent 5D -/-
TS17: head mesenchyme Absent 5D -/- Expression was lost from facial mesenchyme in the mutant.
TS17: forebrain Strong Regionally restricted 5D -/- Expression was absent from the ventral forebrain tissue, and instead was strong in the lateral neuroepithelial tissues of the open neural tube.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory