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Gene Expression Data
Assay Details
Assay
Reference: J:77801 Soo K, et al., Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo. Dev Biol. 2002 Jul 15;247(2):251-70
Assay type: RNA in situ
MGI Accession ID: MGI:5491591
Gene symbol: Pax6
Gene name: paired box 6
Probe: Pax6 probe32
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3C +/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 3C +/+ Expression was detected in the dorsal part.
TS17: telencephalon Present Regionally restricted 3C +/+ Expression was detected in the dorsal part.
TS17: eye Present 3C +/+
Specimen 3C -/-: embryonic day 10.5; Twist1tm1Bhr/Twist1tm1Bhr (more )
Structure Level Pattern Image Note
TS17: forebrain Weak Regionally restricted 3C -/- Much reduced expression was localized to tissues in the lateral margin of the open neural plate.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory