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Gene Expression Data
Assay Details
Assay
Reference: J:64866 Kimura C, et al., Visceral endoderm mediates forebrain development by suppressing posteriorizing signals. Dev Biol. 2000 Sep 15;225(2):304-21
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5489790
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Reporter: lacZ
Direct Detection
Results
Specimen not shown: embryonic day 3.0; Otx2tm2.1Imat/Otx2+ (more )
Note: Morula stage embryo.
Structure Level Pattern Image Note
TS3: compacted morula Absent
Specimen not shown: embryonic day 3.5; Otx2tm2.1Imat/Otx2+ (more )
Note: Blastocyst stage embryo.
Structure Level Pattern Image Note
TS4: blastocyst Absent
Specimen 2D: embryonic day 5.5; Otx2tm2.1Imat/Otx2+ (more )
Structure Level Pattern Image Note
TS7: primitive endoderm Present Regionally restricted 2D Expression was detected in the distal visceral endoderm.
Specimen 2H: embryonic day 5.75; Otx2tm2.1Imat/Otx2+ (more )
Structure Level Pattern Image Note
TS7: primitive endoderm Present Regionally restricted 2H Expression in the distal visceral endoderm had begun to shift to one side.
Specimen 2K: embryonic day 6.0; Otx2tm2.1Imat/Otx2+ (more )
Structure Level Pattern Image Note
TS8: anterior visceral endoderm Present 2K
Specimen 2O: embryonic day 6.25; Otx2tm2.1Imat/Otx2+ (more )
Structure Level Pattern Image Note
TS8: anterior visceral endoderm Present 2O
Specimen 4D: embryonic day 6.5; Otx2tm2.1Imat/Otx2+ (more )
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 4D
TS9: primitive streak Present Regionally restricted 4D Expression was detected in the distal primitive streak but not in the proximal cells.
Specimen 4G: embryonic day 6.5; Otx2tm2.1Imat/Otx2+ (more )
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 4G
TS9: primitive streak Absent 4G Expression was not detected in the proximal cells of the primitive streak.
Specimen 4H: embryonic day 6.5; Otx2tm2.1Imat/Otx2+ (more )
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 4H
TS9: primitive streak Present Regionally restricted 4H Expression was detected in the distal primitive streak cells.
Specimen 4L: embryonic day 7.5; Otx2tm2.1Imat/Otx2+ (more )
Structure Level Pattern Image Note
TS11: definitive endoderm Present Regionally restricted 4L Expression was detected in the anterior definitive endoderm.
TS11: notochordal process Present 4L
TS11: neural ectoderm Present Regionally restricted 4L Expression was detected in the anterior neuroectoderm.
TS11: mesenchyme derived from head mesoderm Absent 4L
Specimen 4O: embryonic day 7.5; Otx2tm2.1Imat/Otx2+ (more )
Structure Level Pattern Image Note
TS11: notochordal process Present 4O
TS11: neural ectoderm Present Regionally restricted 4O Expression was detected in anterior neuroectoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
MGI 6.24 		The Jackson Laboratory