Six1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:119031 Lillevali K, et al., Gata3 is required for early morphogenesis and Fgf10 expression during otic development. Mech Dev. 2006 Jun;123(6):415-29
Assay type:	RNA in situ
MGI Accession ID:	MGI:5486352
Gene symbol:	Six1
Gene name:	sine oculis-related homeobox 1

Probe:	Six1 probe5
Probe preparation:	Antisense labelled with radioactivity RNA

Results

2G ©

Specimen 2G: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: otocyst	Present	Regionally restricted	2G	Expression was detected in the ventral part of the otic vesicle.
TS17: head mesenchyme	Present	Regionally restricted	2G	Expression was detected in the mesenchyme surrounding the otic vesicle.
TS17: endolymphatic appendage	Absent		2G

2H ©

Specimen 2H: embryonic day 10.5; Gata3^tm1Gsv/Gata3^tm1Gsv (more

)
Note: This mutant embryo has two otic vesicles on one side. This section is through the dorsal vesicle.

Structure	Level	Pattern	Image	Note
TS17: otocyst	Absent		2H	In mutant embryos with two vesicles on one side, no expression was detected in the small dorsal vesicle.

2I ©

Specimen 2I: embryonic day 10.5; Gata3^tm1Gsv/Gata3^tm1Gsv (more

)
Note: This mutant embryo has two otic vesicles on one side. This section is through the ventral vesicle.

Structure	Level	Pattern	Image	Note
TS17: otocyst	Strong	Regionally restricted	2I	In mutant embryos with two vesicles on one side, intense expression was detected in the ventral vesicle.
TS17: head mesenchyme	Strong	Regionally restricted	2I	In mutant embryos with two vesicles on one side, intense expression was detected in the mesenchyme surrounding the ventral vesicle.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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