Dlx5 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:119031 Lillevali K, et al., Gata3 is required for early morphogenesis and Fgf10 expression during otic development. Mech Dev. 2006 Jun;123(6):415-29
Assay type:	RNA in situ
MGI Accession ID:	MGI:5486351
Gene symbol:	Dlx5
Gene name:	distal-less homeobox 5

Probe:	Dlx5 probe11
Probe preparation:	Antisense labelled with radioactivity RNA

Results

2D ©

Specimen 2D: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: otocyst epithelium	Strong	Regionally restricted	2D	Expression was strong in the dorsal otic epithelium.
TS17: endolymphatic appendage epithelium	Strong		2D

2E ©

Specimen 2E: embryonic day 10.5; Gata3^tm1Gsv/Gata3^tm1Gsv (more

)
Note: This mutant embryo has two otic vesicles on one side. This section is through the dorsal vesicle.

Structure	Level	Pattern	Image	Note
TS17: otocyst epithelium	Present	Regionally restricted	2E	In mutant embryos with two vesicles on one side, expression was detected mainly in the dorsal vesicle. The level and expression domain was decreased compared to wild type.

2F ©

Specimen 2F: embryonic day 10.5; Gata3^tm1Gsv/Gata3^tm1Gsv (more

)
Note: This mutant embryo has two otic vesicles on one side. This section is through the ventral vesicle.

Structure	Level	Pattern	Image	Note
TS17: otocyst epithelium	Weak	Regionally restricted	2F	In mutant embryos with two vesicles on one side, expression in the ventral vesicle was weaker and more restricted. The level and expression domain was decreased compared to wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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