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Gene Expression Data
Assay Details
Assay
Reference: J:180706 Gruber R, et al., MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway. Nat Cell Biol. 2011 Nov;13(11):1325-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5476798
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: Anti-Ki67
Results
Specimen 2e ctr: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brain Present Regionally restricted 2e Mcph1-ctr Expression was detected in cycling cells.
Specimen 2e del: embryonic day 17.5; Mcph1tm1.1Zqw/Mcph1tm1.1Zqw (more )
Structure Level Pattern Image Note
TS25: brain Present Regionally restricted 2e Mcph1-del Expression was detected in cycling cells. Fewer cells were stained in the mutant.
Specimen 3b ctr: embryonic day 15.5 (more )
Note: Triple labeled: green - Mki67; red - BrdU; blue - DAPI.
Structure Level Pattern Image Note
TS23: brain Present Regionally restricted 3b Mcph1-ctr Expression was detected in cycling cells.
Specimen 3b del: embryonic day 15.5; Mcph1tm1.1Zqw/Mcph1tm1.1Zqw (more )
Note: Triple labeled: green - Mki67; red - BrdU; blue - DAPI.
Structure Level Pattern Image Note
TS23: brain Present Regionally restricted 3b Mcph1-del Expression was detected in cycling cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory