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Gene Expression Data
Assay Details
Assay
Reference: J:134562 Trapp ML, et al., Defects in ciliary localization of Nek8 is associated with cystogenesis. Pediatr Nephrol. 2008 Mar;23(3):377-87
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5475525
Gene symbol: Nek8
Gene name: NIMA (never in mitosis gene a)-related expressed kinase 8
Antibody: anti-Nek8
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: Data was shown in Table 1.
Results
Specimen E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: renal tubule Absent The percentage of the ciliated tubules with expression is 0%.
TS22: cortical renal tubule Absent The percentage of the ciliated tubules with expression is 0%.

Specimen E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: renal tubule Present Regionally restricted Expressed in the luminal cilia. Expressed in 42% medullary dubules, 13% in cortical tubules.
TS23: cortical renal tubule Present Regionally restricted Expressed in the luminal cilia. Expressed in 13% cortical tubules.

Specimen E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: renal tubule Present Regionally restricted Expressed in the luminal cilia. Expressed in 44% medullary dubules, 38% in cortical tubules.
TS24: cortical renal tubule Present Regionally restricted Expressed in the luminal cilia. Expressed in 38% cortical tubules.

Specimen E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: renal tubule Present Regionally restricted Expressed in the luminal cilia. Expressed in 60% medullary dubules, 29% in cortical tubules.
TS26: cortical renal tubule Present Regionally restricted Expressed in the luminal cilia. Expressed in 29% cortical tubules.

Specimen P1: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: renal tubule Present Regionally restricted Expressed in the luminal cilia. Expressed in 72% medullary dubules, 41% in cortical tubules.
TS27: cortical renal tubule Present Regionally restricted Expressed in the luminal cilia. Expressed in 41% cortical tubules.

Specimen P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: renal tubule Present Regionally restricted Expressed in the luminal cilia. Expressed in 66% medullary dubules, 56% in cortical tubules.
TS28: cortical renal tubule Present Regionally restricted Expressed in the luminal cilia. Expressed in 56% cortical tubules.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory