About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:81317 Yamashiro T, et al., Expression of Runx1, -2 and -3 during tooth, palate and craniofacial bone development. Mech Dev. 2002 Dec;119 Suppl 1:S107-10
Assay type: RNA in situ
MGI Accession ID: MGI:5475171
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Probe: Runx2 probe3
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 1B: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: head mesenchyme Present Regionally restricted 1B Expression was intense in mesenchymal condensates of forming bones.
TS21: tooth mesenchyme Present 1B
Specimen 2B: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: jaw primordium mesenchyme Strong Regionally restricted 2B Expression was detected in the dental mesenchyme.
Specimen 2E: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: lower jaw mesenchyme Present Regionally restricted 2E Expression was intense in osteogenic mesenchyme.
TS21: lower jaw tooth mesenchyme Strong 2E
Specimen 2H: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: lower jaw mesenchyme Present Regionally restricted 2H Expression was intense in osteogenic mesenchyme.
TS22: lower jaw tooth mesenchyme Present 2H
Specimen 2K: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: lower jaw mesenchyme Present Regionally restricted 2K Expression was intense in osteogenic mesenchyme.
TS24: lower jaw tooth mesenchyme Strong 2K
Specimen 2N: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: lower jaw Present 2N
TS26: lower jaw tooth mesenchyme Ambiguous 2N Expression was downregulated completely in dental mesenchyme at E18.
Specimen 2Q: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: lower jaw Present 2Q
Specimen 3C: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: lower jaw incisor Present 3C
TS27: lower jaw molar Present 3C
Specimen 3D: postnatal day 2; Runx3tm1Yg/Runx3tm1Yg (more )
Structure Level Pattern Image Note
TS27: lower jaw incisor Present 3D Expression patterns were similar in mutant and wild type mice.
TS27: lower jaw molar Present 3D Expression patterns were similar in mutant and wild type mice.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory