Nog In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:47724 McMahon JA, et al., Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev. 1998 May 15;12(10):1438-52
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:5473697
Gene symbol:	Nog
Gene name:	noggin

Reporter:	lacZ
	Direct Detection

Results

1B ©

Specimen 1B: embryonic day 7.5; Nog^tm1Amc/Nog⁺ (more

)

Structure	Level	Pattern	Image	Note
TS11: node	Present		1B

1F ©

Specimen 1F: embryonic day 9.5; Nog^tm1Amc/Nog⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: migrating neural crest	Present		1F
TS15: notochord	Present		1F
TS15: neural tube	Present	Regionally restricted	1F	Expression in dorsal neural tube.
TS15: tail mesenchyme	Present	Regionally restricted	1F	Expression in ventral posterior mesoderm.

1I ©

Specimen 1I: embryonic day 10.0-10.5; Nog^tm1Amc/Nog⁺ (more

)

Structure	Level	Pattern	Image	Note
TS16: neural tube	Present		1I
TS16: notochord	Present	Regionally restricted	1I	Expression in caudal notochord.
TS16: dorsal root ganglion	Present		1I
TS16: tail mesenchyme	Present	Regionally restricted	1I	Expression in ventral posterior mesoderm.

1K ©

Specimen 1K: embryonic day 10.0-10.5; Nog^tm1Amc/Nog⁺ (more

)

Structure	Level	Pattern	Image	Note
TS16: notochord	Present		1K
TS16: neural tube floor plate	Present	Regionally restricted	1K	Expression in rostral floor plate.

1M ©

Specimen 1M: embryonic day 10.0-10.5; Nog^tm1Amc/Nog⁺ (more

)

Structure	Level	Image
TS16: migrating neural crest	Present	1M
TS16: neural tube	Present	1M
TS16: notochord	Present	1M

1N ©

Specimen 1N: embryonic day 10.0-10.5; Nog^tm1Amc/Nog⁺ (more

)

Structure	Level	Pattern	Image	Note
TS16: neural tube	Present		1N
TS16: notochord	Present		1N
TS16: tail mesenchyme	Present	Regionally restricted	1N	Expression in ventral posterior mesoderm.

3D ©

Specimen 3D: embryonic day 8.5; Nog^tm1Amc/Nog⁺ (more

)
Note: 7-8 somites.

Structure	Level	Pattern	Image	Note
TS13: neural tube	Present	Regionally restricted	3D	Expression in dorsal neural tube.
TS13: notochord	Present		3D

3F ©

Specimen 3F: embryonic day 8.5; Nog^tm1Amc/Nog^tm1Amc (more

)
Note: 7-8 somites.

Structure	Level	Pattern	Image	Note
TS13: neural tube	Present	Regionally restricted	3F	Expression in dorsal neural tube.
TS13: notochord	Present		3F

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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