Gene Expression Data
Assay Details
Assay
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Reference:
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J:47724
McMahon JA, et al., Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev. 1998 May 15;12(10):1438-52
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5473670
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Gene symbol:
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Isl1
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Gene name:
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ISL1 transcription factor, LIM/homeodomain
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Results
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Specimen
6A:
embryonic day 10.5; Nogtm1Amc/Nog +
(more )
Note: Section at level of forelimb bud.
Specimen
6A:
(close )
Genetic Background:
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either: 129 or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Nogtm1Amc/Nog+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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Section at level of forelimb bud.
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: neural tube lateral wall |
Present |
Regionally restricted |
6A
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Expression in differentiating motor neurons extending to hindlimb level.
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Specimen
6B:
embryonic day 10.5; Nogtm1Amc/ Nogtm1Amc
(more )
Note: Section at level of forelimb bud.
Specimen
6B:
(close )
Genetic Background:
|
either: 129/Sv or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Nogtm1Amc/Nogtm1Amc
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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Section at level of forelimb bud.
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Specimen
6C:
embryonic day 10.5; Nogtm1Amc/Nog +
(more )
Note: Section at level of forelimb bud.
Specimen
6C:
(close )
Genetic Background:
|
either: 129 or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Nogtm1Amc/Nog+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
|
Note:
|
Section at level of forelimb bud.
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: neural tube lateral wall |
Present |
Regionally restricted |
6C
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Expression in differentiating motor neurons extending to hindlimb level.
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Specimen
6D:
embryonic day 10.5; Nogtm1Amc/ Nogtm1Amc
(more )
Note: Section at level of forelimb bud.
Specimen
6D:
(close )
Genetic Background:
|
either: 129/Sv or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Nogtm1Amc/Nogtm1Amc
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
|
section
|
Note:
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Section at level of forelimb bud.
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: neural tube lateral wall |
Weak |
Regionally restricted |
6D
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Authors state that motor neuron formation was greatly reduced between limb buds.
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Specimen
6E:
embryonic day 10.5; Nogtm1Amc/Nog +
(more )
Note: Section at level of forelimb bud.
Specimen
6E:
(close )
Genetic Background:
|
either: 129 or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Nogtm1Amc/Nog+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
|
section
|
Note:
|
Section at level of forelimb bud.
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: neural tube lateral wall |
Present |
Regionally restricted |
6E
|
Expression in differentiating motor neurons extending to hindlimb level.
|
Specimen
6F:
embryonic day 10.5; Nogtm1Amc/ Nogtm1Amc
(more )
Note: Section at level of forelimb bud.
Specimen
6F:
(close )
Genetic Background:
|
either: 129/Sv or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Nogtm1Amc/Nogtm1Amc
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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Section at level of forelimb bud.
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