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Gene Expression Data
Assay Details
Assay
Reference: J:29514 Thorsteinsdottir S, et al., Expression patterns of laminin receptor splice variants alpha 6A beta 1 and alpha 6B beta 1 suggest different roles in mouse development. Dev Dyn. 1995 Nov;204(3):240-58
Assay type: RNA in situ
MGI Accession ID: MGI:5469125
Gene symbol: Itga6
Gene name: integrin alpha 6
Probe: alpha6 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 3A: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: chorion Present 3A
TS11: neural ectoderm Present 3A
TS11: parietal endoderm Present 3A
TS11: yolk sac Present 3A
TS28: decidua Present 3A

Specimen 3C,E: embryonic day 8.5 (more )
Note: E: Higher magnification of posterior part of embryo in C
Structure Level Pattern Image Note
TS13: heart Present 3C Expression is in the heart, absent in the endocardium.
TS13: common atrial chamber Strong 3C
TS13: primitive ventricle Present Graded 3C
TS13: cardiac muscle tissue Present 3C , 3E
TS13: hindgut diverticulum Present 3C , 3E
TS13: intermediate mesenchyme Present 3C , 3E
TS13: somite Absent 3E , 3C

Specimen 3G,I: embryonic day 9.5 (more )
Note: I: Higher magnification of posterior part of embryo in G
Structure Level Pattern Image Note
TS15: heart atrium Strong 3G
TS15: heart Present 3G
TS15: primitive ventricle Present 3G
TS15: hindgut epithelium Present 3I , 3G
TS15: myotome Present 3I , 3G
TS15: nephrogenic cord Present 3I , 3G
TS15: tail neural tube floor plate Present 3I , 3G

Specimen Not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Present

Specimen 4A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: heart atrium Strong 4A
TS20: heart ventricle Strong 4A
TS20: epidermis Strong 4A Particularly strong in the mouth and on the snout.
TS20: oral region Strong Regionally restricted 4A Expression is in dental primordia.
TS20: blood vessel Present Regionally restricted 4A Expression is in capillaries in the facial mesenchyme.

Specimen 4B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lens vesicle Strong 4B
TS20: optic stalk Present 4B
TS20: neural retinal epithelium Weak 4B

Specimen 4C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: genital tubercle Strong Regionally restricted 4C Expression is on the tip.
TS20: urogenital sinus Strong Regionally restricted 4C Expression is in urethral epithelium.
TS20: hindgut epithelium Strong Regionally restricted 4C Expression is in distal epithelia.

Specimen 4D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: gonad Strong 4D
TS20: nerve Strong Regionally restricted 4D Expression is in nerves running from the dorsal root ganglia and between the cartilage primordia of the ribs.
TS20: metanephros Present 4D
TS20: mesonephros Weak 4D
TS20: liver Absent 4D

Specimen 4E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: gonad Very strong 4E
TS20: mesonephros Trace 4E
TS20: gland Present Regionally restricted 4E Expression is in the cortex of the adrenal primordium.
TS20: dorsal root ganglion Present 4E
TS20: ganglion Present 4E
TS20: stomach epithelium Present 4E
TS20: spinal cord Present Regionally restricted 4E Expression is in the ependymal layer.

Specimen 4F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Present 4F
TS20: midbrain Present Regionally restricted 4F Expression is in the ependymal layer.

Specimen 4G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: stomach epithelium Very strong 4G

Specimen 4H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: blood vessel Present Regionally restricted 4H Expression is in endothelial cells of capillaries in the snout.
TS20: olfactory epithelium Weak 4H

Specimen Table 1: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cochlea Present
TS20: epidermis Present
TS20: esophagus epithelium Present
TS20: eye Present
TS20: ganglion Present
TS20: genital tubercle Present
TS20: gonad Present
TS20: heart atrium Present
TS20: heart ventricle Present
TS20: hindgut epithelium Present
TS20: intestine epithelium Present
TS20: lung epithelium Present
TS20: olfactory epithelium Present
TS20: stomach epithelium Present
TS20: telencephalon Present
TS20: blood vessel Present Regionally restricted Endothelia.
TS20: midbrain Present Regionally restricted Ependymal layer.
TS20: spinal cord Present Regionally restricted Ependymal layer.
TS20: peripheral nervous system Present Regionally restricted Peripheral nerves.
TS20: metanephros Present Regionally restricted Epithelial tubules.
TS20: oral region Present Regionally restricted Dental primordium.
TS20: gland Present Regionally restricted Adrenal primordium cortex.
TS20: urogenital sinus Present Regionally restricted Urethral epithelium.
TS20: mesonephros Weak Regionally restricted Epithelial tubules.
TS20: endocardial cushion Absent
TS20: liver Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory