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Gene Expression Data
Assay Details
Assay
Reference: J:58583 Fukada K, et al., In situ hybridisation study of type I, II, X collagens and aggrecan mRNas in the developing condylar cartilage of fetal mouse mandible. J Anat. 1999 Oct;195(Pt 3):321-9
Assay type: RNA in situ
MGI Accession ID: MGI:5468299
Gene symbol: Acan
Gene name: aggrecan
Probe: Aggrecan cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1b & 1d: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mandible Present Regionally restricted 1d , 1b Expression was detected adjacent to the ossifying mandibular bone anlage. Expression was also noted in the mesenchymal cell aggregation of the most posterior region.

Specimen 2d: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: mandible Present Regionally restricted 2d Expression was detected in hypertrophic chondrocytes of the cartilage matrix.

Specimen 3d & 4b: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: mandible Present Regionally restricted 4b , 3d Expression was detected from the fibrous cell layer to the bottom of the hypertrophic layer in the condylar cartilage of the mandible. This includes the polymorphic cell layer and the flattened cell layer.

Specimen 5e: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: mandible Ambiguous 5e Expression disappeared in the chondrocytes of the lower half of the hypertrophic cell layer of the condylar cartilage of the mandible.

Specimen 6d: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: tibia-fibula pre-cartilage condensation Present Regionally restricted 6d Expression was detected in the chondrocytes.

Specimen 6i: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: tibia cartilage condensation Present Regionally restricted 6i Expression was detected in the chondrocytes of the cartilage.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory