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Gene Expression Data
Assay Details
Assay
Reference: J:29513 Breier G, et al., Coordinate expression of vascular endothelial growth factor receptor-1 (flt-1) and its ligand suggests a paracrine regulation of murine vascular development. Dev Dyn. 1995 Nov;204(3):228-39
Assay type: RNA in situ
MGI Accession ID: MGI:5467389
Gene symbol: Flt1
Gene name: FMS-like tyrosine kinase 1
Probe: VEGFR1/flt-1 probe
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 2 - embryo: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: yolk sac mesoderm Present 2A/B
TS11: amnion Present 2A/B
TS11: chorion mesoderm Present 2A/B
TS11: ectoplacental cone Present 2A/B Expression is present in proximal cells; this appears as a layer of cells in the ectoplacenta.
TS11: allantois mesoderm Present 2C/D , 2A/B Expression is present in the extra-embryonic mesenchyme in the region of the allantoic bud.
TS11: embryo ectoderm Absent 2C/D , 2A/B
TS11: embryo endoderm Absent 2C/D , 2A/B

Specimen 2 - maternal: postnatal (more )
Structure Level Pattern Image Note
TS28: blood vessel Present Regionally restricted 2A/B Expression is present in the blood vessels of the decidua.
TS28: decidua Present Regionally restricted 2A/B Expression is present in the blood vessels of the decidua.

Specimen 3: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted 3A/B Expression is present in the blood vessels of the decidua.

Specimen 4A-D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: yolk sac mesenchyme Present 4A/B
TS15: spongiotrophoblast Present 4A/B
TS15: dorsal aorta Present 4A/B , 4C/D
TS15: blood vessel Present 4C/D , 4A/B Areas of expression include the perineural vascular plexus in the periphery of the neural tube.
TS15: limb Present 4C/D , 4A/B

Specimen 4E/F: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: yolk sac mesenchyme Present Regionally restricted 4E/F Expression is present in the blood islands, in the perpheral endothelial cell precursors.
TS15: blood Absent 4E/F

Specimen 4G/H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spongiotrophoblast Strong 4G/H There is strong expression in the spongiotrophoblast layer in the outer placenta.
TS22: labyrinthine zone Weak 4G/H There is weak expression in the labyrinthine layer of the inner placenta.

Specimen 5A/B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal aorta Present Regionally restricted 5A/B Expression is present in the inner cell lining (the endothelium).
TS19: blood vessel Present Widespread 5A/B Expression is present in intersomitic capillaries, which sprout from the dorsal aorta, as well as in most, if not all, blood vessels and capillaries of developing organs.

Specimen Not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: blood vessel Present Widespread Expression is present in most, if not all, blood vessels and capillaries of developing organs.

Specimen Not shown: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: blood vessel Present Widespread Expression is present in most, if not all, blood vessels and capillaries of developing organs.

Specimen 5D/F: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: endocardial tissue Present 5D
TS25: blood vessel Present 5F , 5D Areas of the expression include the capillaries of the heart and in blood vessels between the vertebrae and ribs.
TS25: descending aorta Present 5D Expression is present in the endothelium.
TS25: lung Present 5D Expression is present in vascular structures.
TS25: skin Present 5D Expression is present in vascular structures.
TS25: thymus Present 5D Expression is present in vascular structures.

Specimen 5G/H: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: blood vessel Present 5G/H
TS25: heart septum Present 5G/H

Specimen 5K/L: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: blood vessel Present 5K/L Expression is present in the capillaries in the intestinal crypts.

Specimen 5M: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: intestine Present 5M

Specimen 6A/B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: blood vessel Present 6A/B Expression is present in the perineural vascular complex.
TS19: brain Present 6A/B Expression is present in vessels in the neuroectoderm.

Specimen 6C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: blood vessel Present 6C Expression is present in the perineural vascular plexus and in the capillary sprouts in the developing brain.

Specimen 6F/G: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: capillary Present 6F/G Expression is present in capillaries in the brain.

Specimen 6H/I: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: blood vessel Present 6H/I Expression is present in the choroid plexus endothelium.

Specimen Not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Present Expression is present in the endothelium of the choroid plexus.
TS28: choroid plexus Present Expression is present in the endothelium of the choroid plexus.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory