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Gene Expression Data
Assay Details
Assay
Reference: J:189008 Jia Y, et al., Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. Mech Dev. 2012 Sep;129(9-12):193-207
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5466297
Gene symbol: Tgs1
Gene name: trimethylguanosine synthase 1
Antibody: anti-PIMT
Results
Specimen 5C PIMT+/+ (upper): embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: inner cell mass Present Widespread 5C PIMT+/+ Anti-PIMT (upper)
TS4: trophectoderm Present Widespread 5C PIMT+/+ Anti-PIMT (upper)

Specimen 5C PIMT-/- (upper): embryonic day 3.5; Tgs1tm1.2Jkr/Tgs1tm1.2Jkr (more )
Structure Level Pattern Image Note
TS4: inner cell mass Absent 5C PIMT-/- Anti-PIMT (upper)
TS4: trophectoderm Absent 5C PIMT-/- Anti-PIMT (upper)

Specimen 5C PIMT+/+ (center): embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: inner cell mass Present Widespread 5C PIMT+/+ Anti-PIMT (center)
TS4: trophectoderm Present Widespread 5C PIMT+/+ Anti-PIMT (center)

Specimen 5C PIMT-/- (center): embryonic day 3.5; Tgs1tm1.2Jkr/Tgs1tm1.2Jkr (more )
Structure Level Pattern Image Note
TS4: inner cell mass Absent 5C PIMT-/- Anti-PIMT (center)
TS4: trophectoderm Absent 5C PIMT-/- Anti-PIMT (center)

Specimen 5C PIMT+/+ (lower): embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: inner cell mass Present Widespread 5C PIMT+/+ Anti-PIMT (lower)
TS4: trophectoderm Present Widespread 5C PIMT+/+ Anti-PIMT (lower)

Specimen 5C PIMT-/- (lower): embryonic day 3.5; Tgs1tm1.2Jkr/Tgs1tm1.2Jkr (more )
Structure Level Pattern Image Note
TS4: inner cell mass Absent 5C PIMT-/- Anti-PIMT (lower)
TS4: trophectoderm Absent 5C PIMT-/- Anti-PIMT (lower)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory