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Gene Expression Data
Assay Details
Assay
Reference: J:3825 Peters K, et al., Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis. Dev Biol. 1993 Feb;155(2):423-30
Assay type: RNA in situ
MGI Accession ID: MGI:5463787
Gene symbol: Fgfr3
Gene name: fibroblast growth factor receptor 3
Probe: Fgfr-3 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 2A/B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future spinal cord Present Regionally restricted 2A/B Expression was prominant in the germinal epithelium of the spinal cord. Intense expression was in the ventral spinal cord.
TS15: neural tube floor plate Present 2A/B
TS15: limb Absent 2A/B

Specimen 2C/D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 2C/D Expression was prominant in the germinal epithelium of the spinal cord. Intense expression was in the ventral spinal cord.
TS20: spinal cord floor plate Present 2C/D
TS20: vertebral pre-cartilage condensation Present 2C/D

Specimen 2E/F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord Present Regionally restricted 2E/F Expression was detected outside of the germinal epithelium, particularly in the ventral spinal cord.
TS22: vertebral pre-cartilage condensation Present 2E/F

Specimen 3A/B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forebrain Present Regionally restricted 3A/B Expression was detected in the germinal epithelium.

Specimen 3C/D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 3C/D Expression was detected in the germinal epithelium.

Specimen 4A/B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brainstem Present Regionally restricted 4A/B Expression was detected outside the germinal epithelium.

Specimen 4C/D: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: brainstem Present Diffuse 4C/D

Specimen 5A/B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus Absent 5A/B

Specimen 5C/D & 5E & 5F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Present Regionally restricted 5C/D , 5E Expression was limited to cells surrounding the pyramidal cells, possibly Bergmann glia.
TS28: cerebellum granule cell layer Absent 5C/D , 5E
TS28: brainstem nucleus Absent 5C/D , 5F No expression was detected in neurons.
TS28: brainstem Present Regionally restricted 5F , 5C/D The morphology of expressing cells was consistent with glia.

Specimen 6A/B & 6E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cochlear duct Strong Regionally restricted 6E , 6A/B Intense expression was detected in the cochlear duct. Expression was limited to differentiating hair cells and their underlying support cells.

Specimen 6C/D & 6F: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: cochlear duct Present Regionally restricted 6F , 6C/D Expression was detected in hair cells.

Specimen 7A/B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lens Present 7A/B
TS22: cornea Absent 7A/B
TS22: retina Absent 7A/B

Specimen 8A/B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hindlimb skeleton Present Regionally restricted 8A/B In hindlimb long bone, expression was found exclusively in resting cartilage.

Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: blood vessel Absent
TS15: heart Absent
TS15: lung Absent
TS15: foregut Absent Expression was not detected in stomach or intestine.
TS15: visceral organ system Absent Expression was not detected in kidney, liver or spleen.

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: blood vessel Absent
TS22: cochlea Absent
TS22: heart Absent
TS22: intestine Absent
TS22: liver Absent
TS22: lung Absent
TS22: metanephros Absent
TS22: spleen primordium Absent
TS22: stomach Absent

Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lung Trace
TS24: metanephros Trace


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory