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Gene Expression Data
Assay Details
Assay
Reference: J:18124 Edmondson DG, et al., Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis. Development. 1994 May;120(5):1251-63
Assay type: RNA in situ
MGI Accession ID: MGI:5461838
Gene symbol: Mef2c
Gene name: myocyte enhancer factor 2C
Probe: Mef2c probe2
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: Authors state that two probes (MGI:5461731 and MGI:5461732) were used and gave identical in situ hybridization patterns.
Results
Specimen 3A: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: sinus venosus Present 3A

Specimen 3B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: heart Present 3B
TS15: somite Strong Regionally restricted 3B High levels of expression in the rostral somites. Transcripts distributed homogenously throughout the more caudal, less mature somites. No expression in the 11 most caudal somites.
TS15: myotome Present Regionally restricted 3B In older somites, transcripts enriched in regions between or at edges of myotomes.

Specimen 6B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: heart Present 6B
TS17: blood vessel Present Regionally restricted 6B Expression cells that appear to represent blood vessels within the midbrain.

Specimen 6C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: somite Present Regionally restricted 6C In older somites, transcripts enriched in regions between or at edges of myotomes.

Specimen 6E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: heart Present 6E
TS17: myotome Present Regionally restricted 6E Expression initially localized to a group of myocytes in the medial region of the myotome. In older somites, transcripts enriched in regions between or at edges of myotomes.
TS17: somite Present Uniform 6E Transcripts distributed homogenously throughout the more caudal, less mature somites.

Specimen not shown day 10.5 section from whole mount: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: myotome Present

Specimen 6G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: somite Present Regionally restricted 6G Expression beginning to decline in rostral somites.

Specimen not shown day 11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: heart Present

Specimen not shown day 11.5 section from whole mount: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: arterial system Present Regionally restricted Expression in columns of cells that appear to be developing intercostal arteries.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory