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Gene Expression Data
Assay Details
Assay
Reference: J:18124 Edmondson DG, et al., Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis. Development. 1994 May;120(5):1251-63
Assay type: RNA in situ
MGI Accession ID: MGI:5461831
Gene symbol: Mef2a
Gene name: myocyte enhancer factor 2A
Probe: Mef2a probe1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen not shown day 7.5: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Absent

Specimen not shown day 8.5: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: heart Strong

Specimen 4C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: heart Present 4C
TS15: somite Absent 4C
TS15: trunk mesenchyme derived from neural crest Weak Regionally restricted 4C Low levels of expression throughout the lateral mesoderm.
TS15: migrating neural crest Weak Regionally restricted 4C Low levels of expression in neural crest cells migrating away from the neural tube.

Specimen not shown day 10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: myotome Present

Specimen 5C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal aorta Present 5C
TS17: heart Present 5C
TS17: blood vessel Present Regionally restricted 5C Expression in what appear to be blood vessels forming around the neural tube.
TS17: trunk mesenchyme derived from neural crest Present 5C

Specimen not shown day 11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Present Regionally restricted Expression in premuscle masses of the limb buds.
TS19: gut Weak Regionally restricted Low levels of expression in cells contributing to smooth muscle of gut.

Specimen 8C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: skeletal muscle Strong 8C
TS21: tail mesenchyme derived from neural crest Present Regionally restricted 8C Expresssion in neural crest derivatives in the frontonasal region.
TS21: digit mesenchyme Present Regionally restricted 8C Expression in condensing cartilage in limb digirts.

Specimen not shown day 16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: skeletal muscle Strong


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory