Gene Expression Data
Assay Details
Assay
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Reference:
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J:138305
Meyer KD, et al., Immunohistochemical analysis of Disc1 expression in the developing and adult hippocampus. Gene Expr Patterns. 2008 Sep;8(7-8):494-501
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5449036
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Gene symbol:
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Disc1
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Gene name:
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disrupted in schizophrenia 1
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Antibody:
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anti-DISC1 Mid
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Assay notes:
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Authors state that both Disc1 Mid (MGI:5449001) and Disc1 Cterm (MGI:5449004) antibodies were used for all experiments and gave identical expression patterns at all ages tested. (See assay MGI:5449042.)
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Results
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Specimen
2A:
embryonic day 18.0
(more )
Specimen
2A:
(close )
Genetic Background:
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Swiss Webster
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Age:
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embryonic day 18.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: hippocampus |
Present |
Widespread |
2A
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Robust expression throughout the hippocampus. Expression in granule cells precursors moving toward the dentate gyrus.
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Specimen
2B:
embryonic day 18.0
(more )
Specimen
2B:
(close )
Genetic Background:
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Swiss Webster
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Age:
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embryonic day 18.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
2C:
embryonic day 18.0
(more )
Specimen
2C:
(close )
Genetic Background:
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Swiss Webster
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Age:
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embryonic day 18.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
2E:
postnatal day 1
(more )
Specimen
2E:
(close )
Genetic Background:
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Swiss Webster
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
2F:
postnatal day 1
(more )
Specimen
2F:
(close )
Genetic Background:
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Swiss Webster
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
|
section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
2G:
postnatal day 5
(more )
Specimen
2G:
(close )
Genetic Background:
|
Swiss Webster
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Age:
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postnatal day 5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
Paraformaldehyde
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: hippocampus |
Present |
Regionally restricted |
2G
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Well-defined expression pattern in Ammon's horn and the dentate gyrus.
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Specimen
2H:
postnatal day 5
(more )
Specimen
2H:
(close )
Genetic Background:
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Swiss Webster
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Age:
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postnatal day 5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
Paraformaldehyde
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: hippocampus CA3 |
Present |
Regionally restricted |
2H
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Well-defined expression pattern in Ammon's horn and the dentate gyrus.
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Specimen
2I:
postnatal day 5
(more )
Specimen
2I:
(close )
Genetic Background:
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Swiss Webster
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Age:
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postnatal day 5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
Paraformaldehyde
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: dentate gyrus |
Present |
Regionally restricted |
2I
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Well-defined expression pattern in Ammon's horn and the dentate gyrus.
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Specimen
2J:
postnatal day 14
(more )
Specimen
2J:
(close )
Genetic Background:
|
Swiss Webster
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Age:
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postnatal day 14
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Sex:
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Not Specified
|
Type:
|
section
|
Fixation:
|
Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: hippocampus |
Present |
Regionally restricted |
2J
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Well-defined expression pattern in Ammon's horn and the dentate gyrus.
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Specimen
2K:
postnatal day 14
(more )
Specimen
2K:
(close )
Genetic Background:
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Swiss Webster
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Age:
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postnatal day 14
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Sex:
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Not Specified
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Type:
|
section
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Fixation:
|
Paraformaldehyde
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Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: hippocampus CA3 |
Present |
Regionally restricted |
2K
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Well-defined expression pattern in Ammon's horn and the dentate gyrus.
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Specimen
2L:
postnatal day 14
(more )
Specimen
2L:
(close )
Genetic Background:
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Swiss Webster
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Age:
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postnatal day 14
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Sex:
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Not Specified
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Type:
|
section
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Fixation:
|
Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: dentate gyrus |
Present |
Regionally restricted |
2L
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Well-defined expression pattern in Ammon's horn and the dentate gyrus.
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Specimen
3A/C:
postnatal day 7
(more )
Specimen
3A/C:
(close )
Genetic Background:
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Swiss Webster
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Age:
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postnatal day 7
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
3D/F:
postnatal week 6
(more )
Specimen
3D/F:
(close )
Genetic Background:
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Swiss Webster
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
3G/I:
postnatal adult
(more )
Specimen
3G/I:
(close )
Genetic Background:
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Swiss Webster
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
4A/C:
postnatal week 14
(more )
Specimen
4A/C:
(close )
Genetic Background:
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Swiss Webster
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Age:
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postnatal week 14
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
5A/C:
postnatal week 10
(more )
Specimen
5A/C:
(close )
Genetic Background:
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Swiss Webster
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Age:
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postnatal week 10
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
Paraformaldehyde
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: dentate gyrus |
Present |
Regionally restricted |
5A
,
5C
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Expression in interneurons at the base of the granule cell layers.
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Specimen
5D/F:
postnatal week 10
(more )
Specimen
5D/F:
(close )
Genetic Background:
|
Swiss Webster
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Age:
|
postnatal week 10
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Sex:
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Not Specified
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Type:
|
section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
6A:
postnatal week 10
(more )
Specimen
6A:
(close )
Genetic Background:
|
Swiss Webster
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Age:
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postnatal week 10
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Sex:
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Not Specified
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Type:
|
section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
6B:
postnatal day 7
(more )
Specimen
6B:
(close )
Genetic Background:
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Swiss Webster
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Age:
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postnatal day 7
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Sex:
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Not Specified
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Type:
|
section
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Fixation:
|
Paraformaldehyde
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Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: hippocampus CA3 |
Present |
Regionally restricted |
6B
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Expression in CA3 pyramidal neurons in a distinct perinuclear pattern, extending slightly into the proximal region of dendrites.
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TS28: hippocampus pyramidal cell layer |
Present |
Regionally restricted |
6B
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Expression in CA3 pyramidal neurons in a distinct perinuclear pattern, extending slightly into the proximal region of dendrites.
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Specimen
6C:
postnatal week 14
(more )
Specimen
6C:
(close )
Genetic Background:
|
Swiss Webster
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Age:
|
postnatal week 14
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Sex:
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Not Specified
|
Type:
|
section
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Fixation:
|
Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: hippocampus CA3 |
Present |
Regionally restricted |
6C
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Expression in CA3 pyramidal neurons in a distinct perinuclear pattern. Authors state that much of the expression in dendritic extensions is lost.
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TS28: hippocampus pyramidal cell layer |
Present |
Regionally restricted |
6C
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Expression in CA3 pyramidal neurons in a distinct perinuclear pattern. Authors state that much of the expression in dendritic extensions is lost.
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