About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:130176 Nammo T, et al., Expression of HNF-4alpha (MODY1), HNF-1beta (MODY5), and HNF-1alpha (MODY3) proteins in the developing mouse pancreas. Gene Expr Patterns. 2008 Jan;8(2):96-106
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5448228
Gene symbol: Hnf4a
Gene name: hepatic nuclear factor 4, alpha
Antibody: anti-HNF4a (clone H1415)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: pancreas primordium Present Regionally restricted 1A Expression in most epithelial cells of the pancreatic bud. Constant level of expression in most pancreatic cells; strong expression in a few cells.

Specimen 1B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: pancreas primordium Present Non-Uniform 1B Constant level of expression in most pancreatic cells; strong expression in a few cells.

Specimen 1C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: pancreas primordium Present Regionally restricted 1C Constant level of expression in most pancreatic cells; strong expression in a few cells. Expresssion was more intense by E11.5.

Specimen 1D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pancreas Present Regionally restricted 1D Constant level of expression in most pancreatic cells; strong expression in a few cells. Expression in cells with branching epithelial structures.

Specimen 1E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pancreas Present Regionally restricted 1E Constant level of expression in most pancreatic cells; strong expression in a few cells. Expression in cells with branching epithelial structures.

Specimen 1F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: pancreas Present Regionally restricted 1F Strong expression in differentiated acinar cells with a polarized appearance; weak expression in duct-like epithelium. Strong expression in a few cells within islet-like cell clusters.

Specimen 1G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: pancreas Present Regionally restricted 1G Strong expression in differentiated acinar cells with a polarized appearance; weak expression in duct-like epithelium. Strong expression in a few cells within islet-like cell clusters.

Specimen 1H: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: pancreas Present Regionally restricted 1H Weak expression in ductal cells and most of the islet cells. Strong expression in a few cells located at the periphery of the islets.

Specimen 1I: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: pancreatic duct Weak 1I
TS28: islets of Langerhans Present Regionally restricted 1I Weak expression in most of the islet cells. Strong expression in a few cells located at the periphery of the islets.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory