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Gene Expression Data
Assay Details
Assay
Reference: J:73806 den Hollander AI, et al., Isolation of Crb1, a mouse homologue of Drosophila crumbs, and analysis of its expression pattern in eye and brain. Mech Dev. 2002 Jan;110(1-2):203-7
Assay type: RNA in situ
MGI Accession ID: MGI:5447428
Gene symbol: Crb1
Gene name: crumbs family member 1, photoreceptor morphogenesis associated
Probe: Crb1 cDNA2
Probe preparation: Antisense labelled with S35 RNA
Assay notes: The authors state that they used two probes but did not specify which one was used for these specimens: Crb1 cDNA1 (MGI:5447419) or Crb1 cDNA2 (MGI:5447421).
Results
Specimen Not shown E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: retina Present

Specimen 2A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: retina Present 2A Expression is in the proliferative retinoblasts.

Specimen 2B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: retina Present 2B Expression is in the proliferative retinoblasts.

Specimen 2C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: retina Present 2C Expression is in the proliferative retinoblasts.

Specimen 2D: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer Strong 2D
TS28: retina outer nuclear layer Present 2D
TS28: retina inner nuclear layer Present Single cells 2D

Specimen 2E: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer Strong 2E
TS28: retina outer nuclear layer Present 2E
TS28: retina inner nuclear layer Present Single cells 2E

Specimen 2G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: iris Strong 2G

Specimen 2I: postnatal adult (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer Strong 2I
TS28: retina outer nuclear layer Present 2I
TS28: retina inner nuclear layer Present Single cells 2I

Specimen 3A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 3A Expression is ventral.
TS17: neural tube Present Regionally restricted 3A Expression is ventral.
TS17: diencephalon Present Regionally restricted 3A Expression is in the mammillary and hypothalamic area.
TS17: head Present Regionally restricted 3A Expression is in the optic area.
TS17: forebrain Present Regionally restricted 3A Expression is in the zona limitans intrathalamica.
TS17: telencephalon Absent 3A

Specimen 3D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 3D Expression is in the V3 interneurons placed between the floor plate and the motorneurons all along the spinal cord axis.

Specimen 4B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: adenohypophysis pars tuberalis Present 4B
TS20: diencephalon Present Regionally restricted 4B
TS20: hypothalamus Present Regionally restricted 4B Expression is in the mammillary and tuberalis regions.
TS20: thalamus Present Regionally restricted 4B Expression is in the dorsal thalamus.

Specimen 4D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: adenohypophysis pars tuberalis Present 4D
TS22: diencephalon Present Regionally restricted 4D
TS22: hypothalamus Present Regionally restricted 4D Expression is in the mammillary and tuberalis regions.
TS22: thalamus Present Regionally restricted 4D Expression is in the dorsal thalamus.

Specimen 4G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: head Present Regionally restricted 4G Expression is in the preoptic area.
TS24: thalamus Present Regionally restricted 4G Expression is in the dorsal thalamus.

Specimen 4I: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hypothalamus Present 4I Expression is in the mammillary and tuberalis regions.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory