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Gene Expression Data
Assay Details
Assay
Reference: J:75699 Albrecht AN, et al., The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67
Assay type: RNA in situ
MGI Accession ID: MGI:5446503
Gene symbol: Nog
Gene name: noggin
Probe: Nog probe9
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen not shown 13.5 wt: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hand pre-cartilage condensation Present Widespread Expression throughout cartilaginous anlagen.

Specimen not shown 13.5 spdh/spdh: embryonic day 13.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS21: hand Present

Specimen 5 Noggin 14.5 wt: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forelimb phalanx cartilage condensation Present Widespread 5_Noggin 14.5 wt Expression throughout cartilaginous anlagen.

Specimen 5 Noggin 14.5 spdh/spdh: embryonic day 14.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS22: forelimb phalanx cartilage condensation Present Widespread 5_Noggin 14.5 spdh/spdh Persistent expression throughout cartilage anlagen.

Specimen 5 Noggin 16.5 wt: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: forelimb digit mesenchyme Present Regionally restricted 5_Noggin 16.5 wt Expression restricted to cartilage flanking the joints.

Specimen 5 Noggin 16.5 spdh/spdh: embryonic day 16.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS24: forelimb phalanx Absent 5_Noggin 16.5 spdh/spdh Expresssion disappeared from phalanges.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory