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Gene Expression Data
Assay Details
Assay
Reference: J:75699 Albrecht AN, et al., The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67
Assay type: RNA in situ
MGI Accession ID: MGI:5446498
Gene symbol: Ihh
Gene name: Indian hedgehog
Probe: Ihh cDNA10
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen 4 Ihh 13.5 wt: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb phalanx pre-cartilage condensation Present Regionally restricted 4_Ihh 13.5 wt Expression in pre-hypertrophic chondrocytes and also in digital anlagen. Expression at three sites in each phalangeal anlagen.
Specimen 4 Ihh 13.5 spdh/spdh: embryonic day 13.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS21: hand Strong Regionally restricted 4_Ihh 13.5 spdh/spdh
Specimen 4 Ihh 14.5 wt: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hand Present 4_Ihh 14.5 wt
Specimen 4 Ihh 14.5 spdh/spdh: embryonic day 14.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS22: hand Present Regionally restricted 4_Ihh 14.5 spdh/spdh Expression domains partially fused with each other.
Specimen 4 Ihh 16.5 wt: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hand Present 4_Ihh 16.5 wt
Specimen 4 Ihh 16.5 spdh/spdh: embryonic day 16.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS24: hand Trace Regionally restricted 4_Ihh 16.5 spdh/spdh Expression was completely absent, except for digit 1 and distal phalanges that were somewhat spared.
Specimen 4 Ihh Newborn wt: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: hand bone Present 4_Ihh Newborn wt
Specimen 4 Ihh Newborn spdh/spdh: postnatal newborn; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS27: hand connective tissue Present Regionally restricted 4_Ihh Newborn spdh/spdh Expression at sides of bones in ectopic areas of ossification.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory